ID B7N8C2_ECOLU Unreviewed; 326 AA.
AC B7N8C2;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 96.
DE SubName: Full=Lateral flagellar RpoN-interacting regulatory protein {ECO:0000313|EMBL:CAR11472.1};
GN Name=lafK {ECO:0000313|EMBL:CAR11472.1};
GN OrderedLocusNames=ECUMN_0257 {ECO:0000313|EMBL:CAR11472.1};
OS Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=585056 {ECO:0000313|EMBL:CAR11472.1, ECO:0000313|Proteomes:UP000007097};
RN [1] {ECO:0000313|Proteomes:UP000007097}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UMN026 / ExPEC {ECO:0000313|Proteomes:UP000007097};
RX PubMed=19165319; DOI=10.1371/journal.pgen.1000344;
RA Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P.,
RA Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H.,
RA Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E.,
RA Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C.,
RA Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S.,
RA Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J.,
RA Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E.;
RT "Organised genome dynamics in the Escherichia coli species results in
RT highly diverse adaptive paths.";
RL PLoS Genet. 5:E1000344-E1000344(2009).
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DR EMBL; CU928163; CAR11472.1; -; Genomic_DNA.
DR RefSeq; WP_001292195.1; NC_011751.1.
DR RefSeq; YP_002411028.1; NC_011751.1.
DR AlphaFoldDB; B7N8C2; -.
DR STRING; 585056.ECUMN_0257; -.
DR KEGG; eum:ECUMN_0257; -.
DR PATRIC; fig|585056.7.peg.449; -.
DR HOGENOM; CLU_000445_0_7_6; -.
DR Proteomes; UP000007097; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR InterPro; IPR025944; Sigma_54_int_dom_CS.
DR PANTHER; PTHR32071:SF21; PROPIONATE CATABOLISM OPERON REGULATORY PROTEIN; 1.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF02954; HTH_8; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR PRINTS; PR01590; HTHFIS.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR PROSITE; PS00688; SIGMA54_INTERACT_3; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell projection {ECO:0000313|EMBL:CAR11472.1};
KW Cilium {ECO:0000313|EMBL:CAR11472.1};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Flagellum {ECO:0000313|EMBL:CAR11472.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 4..232
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
SQ SEQUENCE 326 AA; 36025 MW; 89898376206EFE5B CRC64;
MSELIATAAS SINAFTLAKR VAAFNVPVLI QGETGAGKEC VAKYIHSVAF GENAPYIGVN
CAAIPENMLE ATLFGYDKGA FTGAIASVPG KMELANNGTL LLDEIGDMPL ALQAKILRVL
QEQQVERLGS NRQIKLNFRL IACTNKNLEQ EVAAGRFRED LYYRLAVIPI TMPPLRERLN
DIIPLAESFI KKYSTVLVKN ITLSESTRRA LLNYRWPGNV RQLENAIQRG MILNRDGVIF
PDALGLPEID VADHSELQWP VQPSVSVAET SDLGQAGRSA QYQYIADLMR KYQGNRSKIA
DLLGITPRAL RYRLASMRKQ GIEVFS
//
