ID B7PB35_IXOSC Unreviewed; 412 AA.
AC B7PB35;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Sulfotransferase, putative {ECO:0000313|EMBL:EEC03807.1, ECO:0000313|EnsemblMetazoa:ISCW002210-PA};
DE EC=2.8.2.2 {ECO:0000313|EMBL:EEC03807.1};
GN ORFNames=IscW_ISCW002210 {ECO:0000313|EMBL:EEC03807.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC03807.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC03807.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW002210-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW002210-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the sulfotransferase 1 family.
CC {ECO:0000256|ARBA:ARBA00005771}.
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DR EMBL; ABJB010047596; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010505545; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010877078; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010975139; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS674364; EEC03807.1; -; Genomic_DNA.
DR RefSeq; XP_002407648.1; XM_002407604.1.
DR AlphaFoldDB; B7PB35; -.
DR PaxDb; 6945-B7PB35; -.
DR EnsemblMetazoa; ISCW002210-RA; ISCW002210-PA; ISCW002210.
DR KEGG; isc:IscW_ISCW002210; -.
DR VEuPathDB; VectorBase:ISCI002210; -.
DR VEuPathDB; VectorBase:ISCP_038341; -.
DR VEuPathDB; VectorBase:ISCW002210; -.
DR HOGENOM; CLU_027239_2_0_1; -.
DR InParanoid; B7PB35; -.
DR OMA; ICAKHET; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0004027; F:alcohol sulfotransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0008146; F:sulfotransferase activity; IBA:GO_Central.
DR GO; GO:0051923; P:sulfation; IBA:GO_Central.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000863; Sulfotransferase_dom.
DR PANTHER; PTHR11783:SF334; SULFOTRANSFERASE SSU-1; 1.
DR PANTHER; PTHR11783; SULFOTRANSFERASE SULT; 1.
DR Pfam; PF00685; Sulfotransfer_1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EEC03807.1}.
FT DOMAIN 125..389
FT /note="Sulfotransferase"
FT /evidence="ECO:0000259|Pfam:PF00685"
SQ SEQUENCE 412 AA; 47209 MW; 2BA56917DE6889A1 CRC64;
MTGYNEITKA FRLARRTLPP PSDKLDRAQA VAFRQLQTRT KGIKECSLHF GNLGLIAAAA
ELTIRRESTQ ICFAFTVLKP TSAGKQHSMS PKKLPAYQVI DGLRVSTVFT EEMIRDALNF
KTGPGDVVLA TFPKCGTHWL QQVVQLIMNK GQSANDWSEF WNGAPVLEMG WAKTLEKIPA
PRVMQTHIPL HRLHYNPATK YVYLVRNPKD CCVSFFHHTR MLPEYQFQDG SFDDFFKLFL
KGETDHGDYF DHVMSWYAHK DDPNVFFCTY EDLKKHTRDV VLKLAHFLGQ EYGKLLEENE
DVLNQVLEKS SVQFMKDAFD SWNQKLERAF AKDSSVIPEG MKKFLLDDSG KFAASNLVRK
GEVGNWKTLF SADHSRRLQE RINEKTKGSD VMSLWAVCGQ PRASENERQK AR
//
