ID B7PBU8_IXOSC Unreviewed; 322 AA.
AC B7PBU8;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE SubName: Full=Apoptosis-promoting RNA-binding protein TIA-1/TIAR, putative {ECO:0000313|EMBL:EEC04070.1, ECO:0000313|EnsemblMetazoa:ISCW016601-PA};
GN ORFNames=IscW_ISCW016601 {ECO:0000313|EMBL:EEC04070.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC04070.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC04070.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW016601-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW016601-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; ABJB010127132; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010452482; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010697062; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010846203; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB011020168; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB011021500; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS679392; EEC04070.1; -; Genomic_DNA.
DR RefSeq; XP_002408889.1; XM_002408845.1.
DR AlphaFoldDB; B7PBU8; -.
DR STRING; 6945.B7PBU8; -.
DR PaxDb; 6945-B7PBU8; -.
DR EnsemblMetazoa; ISCW016601-RA; ISCW016601-PA; ISCW016601.
DR KEGG; isc:IscW_ISCW016601; -.
DR VEuPathDB; VectorBase:ISCI016601; -.
DR VEuPathDB; VectorBase:ISCP_037599; -.
DR VEuPathDB; VectorBase:ISCW016601; -.
DR HOGENOM; CLU_025000_3_0_1; -.
DR InParanoid; B7PBU8; -.
DR OMA; RGKSMKC; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.70.330; -; 3.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR48038; RIBONUCLEOPROTEIN RB97D; 1.
DR PANTHER; PTHR48038:SF1; RIBONUCLEOPROTEIN RB97D; 1.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS50102; RRM; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|PeptideAtlas:B7PBU8};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 153..219
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
SQ SEQUENCE 322 AA; 35472 MW; AB9BECE885010A88 CRC64;
MLFFFSLFQE MKVNWATSPG NTPKLDTSKH YHIFVGDLSP EIETTQLRDA FAPFGEISIM
TLRGVPNNTD LKEARFYYRW MLGICQGRAP SGSGFSRTLA ACSLSIRAAT RPPTSLITGL
PLALLGSANS AEFVPGGATA LGMNFDCCCF FELSRFVLAE ELMQKTFNTY GAIQEIRVFK
DKGYAFVRFA TKEAATHAIV ATHNSDVNGQ TVKCSWGKEA GDPNNQQQPQ NLATQYSYPY
QQMGYWYPQA AAGYPQVQGQ FMQGVQYPYS QYYGQGFGGV GMQMAWQGLP GQPPVAAQTA
MAQGLQQPGM IGAYPMQQYQ AQ
//
