ID B7PDG7_IXOSC Unreviewed; 1062 AA.
AC B7PDG7;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Factor for adipocyte differentiation, putative {ECO:0000313|EMBL:EEC04639.1, ECO:0000313|EnsemblMetazoa:ISCW016933-PA};
DE EC=3.2.1.91 {ECO:0000313|EMBL:EEC04639.1};
GN ORFNames=IscW_ISCW016933 {ECO:0000313|EMBL:EEC04639.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC04639.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC04639.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW016933-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW016933-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the FNDC3 family.
CC {ECO:0000256|ARBA:ARBA00038207}.
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DR EMBL; ABJB010002987; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010033163; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010154141; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010176868; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010265514; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010280189; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010366722; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010598280; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010641371; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010759269; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS689861; EEC04639.1; -; Genomic_DNA.
DR RefSeq; XP_002410801.1; XM_002410756.1.
DR AlphaFoldDB; B7PDG7; -.
DR STRING; 6945.B7PDG7; -.
DR PaxDb; 6945-B7PDG7; -.
DR EnsemblMetazoa; ISCW016933-RA; ISCW016933-PA; ISCW016933.
DR KEGG; isc:IscW_ISCW016933; -.
DR VEuPathDB; VectorBase:ISCI016933; -.
DR VEuPathDB; VectorBase:ISCP_006435; -.
DR VEuPathDB; VectorBase:ISCW016933; -.
DR HOGENOM; CLU_004152_0_0_1; -.
DR InParanoid; B7PDG7; -.
DR OMA; DTHFEIR; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016162; F:cellulose 1,4-beta-cellobiosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 7.
DR Gene3D; 2.60.40.10; Immunoglobulins; 8.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR24099; E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED; 1.
DR PANTHER; PTHR24099:SF11; FIBRONECTIN TYPE III DOMAIN-CONTAINING 3BA-RELATED; 1.
DR Pfam; PF00041; fn3; 5.
DR PRINTS; PR00014; FNTYPEIII.
DR SMART; SM00060; FN3; 8.
DR SUPFAM; SSF49265; Fibronectin type III; 4.
DR PROSITE; PS50853; FN3; 7.
PE 1: Evidence at protein level;
KW Glycosidase {ECO:0000313|EMBL:EEC04639.1};
KW Hydrolase {ECO:0000313|EMBL:EEC04639.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Proteomics identification {ECO:0007829|PeptideAtlas:B7PDG7};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1035..1054
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 303..391
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 395..486
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 490..591
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 593..689
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 690..804
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 805..895
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 899..997
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 96..169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 374..421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 734..756
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 877..908
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 128..146
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 147..169
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1062 AA; 111396 MW; 7F3D1CA9B63ABDFA CRC64;
MVSNSTTPPM AVPVQVPPGH VVQQIVDENG TLRHIILSPQ PQHVTLPTVA TPYTGAPGGA
PPPAQPAAAF FPYTAPTPGA PAGLQFAGQF HSAMQAPLGA SPHSPQGHAV PGVVPQQQPP
QGVVPPPHKD ERSQKQALKL RKKLESRQGP SSSSLGAPSS GARSDSSSPK SDIALRALLS
SLSAPAVSQV GAREATAEWS APVANAAPAP KEGEVAAAAD GASSTAASSA AATPAAPPPA
PSLEEVSYEL LLSEKGQDRP ARLLKCGKVL RSKLEDLKPA TEYILCPWSS TCRLTTCGAA
PVPPEPPVVG QVTASSAALE WDCRATDDSF TLSLEQEGSQ HGFIPVYNGS ETRFTCQRLI
RNTEYRVRLV AHNEEGSSGP SRVTSLRTLP DRPGRPARPS AKGRIRSHNF TASWEPPKDD
GGSEITRYSL QMDSGNGFEE VYAGPDRDHV CSGLEPGATY RLRVNCSSAG GVSDFSEVSS
VATLPLCPGA CDPPRMHGKA RAISTHIKWA PPAYDGGSPV TEFELQVAAA PDPESEARKE
PRVAYRGPDW DCTVAGLLPG RPYLYSVRAF NSAGAGPWSE PLHALSGSGP PDAPRGLSVQ
ARSASCALVS WEEATCHGAP VSEYLLECRQ PETAASGATT FAQLYSGRTA HFEAKGLEPA
SCYCFRVQAV SSAGPSPFSD AVEFVTPPGV PGPVGSLECV RGHTSLELTW AQPPCHGSDI
THYVVEVTEM GPLSSSSASA ASPAATSTSF SPASTHVAET TRLSVSSLRP ETAYKVRVQA
VNGVGSGPLS SPALRTSTRA LPPPAPSLEC LGATHSSLRL RWGDQAEKSL RDFVQYTLEM
EVKPGLFAVL YQGPSHSYKA SRLQENHPYR FRIQATSDAG EGPHSEPATF STTRALPPAP
KAPRVTPQGD TSCLLEWQAV RLLTDDPVSY LVQLQQSGSS EFSVVYRDYD TRCSLSNLSP
HTFHCARVAA VRHCPQSPEP LCGPYGPATS FQLFAEPAAG NGGSSQVGAS ASATSGWSLQ
GSRSGLLPSL GDQQWAGILV GGFTLLAVLA AVLLQEVVAR NQ
//
