ID B7PK00_IXOSC Unreviewed; 537 AA.
AC B7PK00;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Na+/dicarboxylate, Na+/tricarboxylate and phosphate transporter, putative {ECO:0000313|EMBL:EEC06922.1, ECO:0000313|EnsemblMetazoa:ISCW003456-PA};
DE Flags: Fragment;
GN ORFNames=IscW_ISCW003456 {ECO:0000313|EMBL:EEC06922.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC06922.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC06922.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW003456-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW003456-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family.
CC NADC subfamily. {ECO:0000256|ARBA:ARBA00006772}.
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DR EMBL; ABJB010046736; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010064096; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010175083; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010390377; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010398848; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010432721; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010502262; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010765160; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010942937; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB011112226; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS729550; EEC06922.1; -; Genomic_DNA.
DR RefSeq; XP_002408980.1; XM_002408936.1.
DR AlphaFoldDB; B7PK00; -.
DR STRING; 6945.B7PK00; -.
DR PaxDb; 6945-B7PK00; -.
DR EnsemblMetazoa; ISCW003456-RA; ISCW003456-PA; ISCW003456.
DR KEGG; isc:IscW_ISCW003456; -.
DR VEuPathDB; VectorBase:ISCI003456; -.
DR VEuPathDB; VectorBase:ISCP_031997; -.
DR VEuPathDB; VectorBase:ISCW003456; -.
DR HOGENOM; CLU_005170_0_0_1; -.
DR InParanoid; B7PK00; -.
DR OMA; IWWMTEA; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015137; F:citrate transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0015141; F:succinate transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0015746; P:citrate transport; IBA:GO_Central.
DR InterPro; IPR001898; SLC13A/DASS.
DR PANTHER; PTHR10283:SF82; PROTEIN I'M NOT DEAD YET-RELATED; 1.
DR PANTHER; PTHR10283; SOLUTE CARRIER FAMILY 13 MEMBER; 1.
DR Pfam; PF00939; Na_sulph_symp; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 59..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 124..143
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 233..252
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..312
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 333..349
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 408..431
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 451..481
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 493..515
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EEC06922.1"
FT NON_TER 537
FT /evidence="ECO:0000313|EMBL:EEC06922.1"
SQ SEQUENCE 537 AA; 59176 MW; CA4D72255D2A9F40 CRC64;
LKKTHMFLRS LRRSWRLLYV ILVPLLLLPI PFSLGGKAGW CAYILLWMAF YWTAEAIPLP
VTSFMPVILF PLFGILSSAK VSTFYLNVSI IRLETGKGTF RLLLLKTLPW FKCALSRCFT
KDALYCRLLL GFMLVTMFLS MWIPNTASTS IMAPIVMAVV DQMHASSKLY KNHPERTEDA
GKVLMRKTML LSVAYAANIG GTGSLIGTAP NLVLKGLFEE LFPMSTELTF ATWMLYNVPT
MILCVLLAWI YLQWTARSAL LLCSNIPAPI IFRAELLRSL SLAEIFSPYP FSFPETAVLS
LMITMIILWF TLKPQIFTGW VELFPYAKMI KPTVPAMAIT FLLFIIPKNP RSPSTSPPLL
TWEEANEKAQ WGIAILIGGG MCLAEASKAS GLSSILVENL KSLEVLPTAL TALILCFAAS
MFTEITSNTA VSSILLPVVC EMAVALQVHP LYLALPVTIG CSFSFMLPAA TPPNAIVFGL
AKLKILDMAK PGFIMNTICV LVEVAMIHAL GFPIFGLTTY PSWADHPKSG SGAVANN
//
