ID B7PMP6_IXOSC Unreviewed; 925 AA.
AC B7PMP6;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE SubName: Full=AP-3 complex subunit delta-1, putative {ECO:0000313|EMBL:EEC07868.1, ECO:0000313|EnsemblMetazoa:ISCW018459-PA};
DE Flags: Fragment;
GN ORFNames=IscW_ISCW018459 {ECO:0000313|EMBL:EEC07868.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC07868.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC07868.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW018459-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW018459-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the adaptor complexes large subunit family.
CC {ECO:0000256|ARBA:ARBA00006613}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ABJB010205254; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010278606; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010288301; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010374283; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010674295; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010758244; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010853523; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010898141; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB011027868; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB011118494; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS748754; EEC07868.1; -; Genomic_DNA.
DR RefSeq; XP_002435044.1; XM_002434999.1.
DR AlphaFoldDB; B7PMP6; -.
DR STRING; 6945.B7PMP6; -.
DR PaxDb; 6945-B7PMP6; -.
DR EnsemblMetazoa; ISCW018459-RA; ISCW018459-PA; ISCW018459.
DR KEGG; isc:IscW_ISCW018459; -.
DR VEuPathDB; VectorBase:ISCI018459; -.
DR VEuPathDB; VectorBase:ISCP_001893; -.
DR VEuPathDB; VectorBase:ISCW018459; -.
DR HOGENOM; CLU_001908_0_0_1; -.
DR InParanoid; B7PMP6; -.
DR OMA; AYLQMMG; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0030123; C:AP-3 adaptor complex; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.30.450.50; Longin domain; 1.
DR InterPro; IPR017105; AP3_complex_dsu.
DR InterPro; IPR010474; AP3D_dom_metazoa.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR PANTHER; PTHR22781:SF12; AP-3 COMPLEX SUBUNIT DELTA-1; 1.
DR PANTHER; PTHR22781; DELTA ADAPTIN-RELATED; 1.
DR Pfam; PF01602; Adaptin_N; 1.
DR Pfam; PF06375; AP3D1; 1.
DR SMART; SM01354; BLVR; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|PeptideAtlas:B7PMP6};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555}.
FT DOMAIN 427..583
FT /note="AP-3 complex subunit delta"
FT /evidence="ECO:0000259|SMART:SM01354"
FT REGION 495..686
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 495..512
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 522..539
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 558..605
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 629..650
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EEC07868.1"
SQ SEQUENCE 925 AA; 103699 MW; 18CB1D3700B7007E CRC64;
FGALTPLEPR LGKKLIEPLT NLIHSTSAMS LLYECINTVI AVLISISSGM PNHSASIQLC
VQKLRILIED SDQNLKYLGL LAMSKILRTH PKSVQAHKDL VLQCLDDKDE SIRLRALDLL
YGMVSKKNLM EIVKKLMVHM DRAEGSAYRD ELLSKVIDIC SQNNYQYITN FEWYVSVLVE
LTRIEGTKHG LTIASQMMDV AVRVQAVRAF SVSQMAVLLE NTHLLVGNGQ RNSICEVLYA
AAWICGEYSD LLEDPRSSLD SLLRPRACVL PPHIQSAYVH NALKLWARML AQEERANLGD
SESSLSEGGQ EACTLLCQRL PLFVHSGDLE VQERACCALH LVRQVSKMQA RGERVGEELR
ALFAGDLNPV APKAQKKVPL PEGGKESVYE KAICDFFNTM WKAWEPRELG PAKARPTREK
NCREPLAAPF PLAQMREARK QEQANNPHYL KATPKSRSSN GHIQGVGVED IPVAEIDLSV
PLHIPGLISS DKYLSASRKA REVADGEEGG DRRKKKKKRR RRKGEEEEEE KRPPPEVPSE
EELPAEAVNT SLGEMPEGAR LTDDEDDDRH KDDPHRALDI DLEHDPVHAR CRPLHEERPP
RHQDHPSVLP DVTPEVEEPQ DGPRLHKRDG DRKHRKKKKE HRHKSKERKH RRREESPPVN
AVTETVDREE SAGDAPATHA KCVSSPQPAS NYKLLADDQN VKLVYEVRPL PGVVNQVVVS
IIFTNQSSCQ LKEMELGILD TLNTKLVRGV DSHDGVKVPF QLPPCTANEG QFAFTVDSVS
MAQRLRGTFT YMLVTDTGST HEKLDFKLHL PVSSYLIGTM YKRDTFAELL RGGELSAKSG
FTLDSVEFEF SHVLSKICFH CHFTVVEQVE LSASLYSRSI QDDHICLLVK HMNPNRLHVD
GKSTNGQLLS SLMDEVRALL SASAS
//
