ID B7PMX8_IXOSC Unreviewed; 401 AA.
AC B7PMX8;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 24-JAN-2024, entry version 83.
DE SubName: Full=Sperm protein, putative {ECO:0000313|EMBL:EEC07950.1, ECO:0000313|EnsemblMetazoa:ISCW005633-PA};
DE Flags: Fragment;
GN ORFNames=IscW_ISCW005633 {ECO:0000313|EMBL:EEC07950.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC07950.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC07950.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW005633-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW005633-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR EMBL; ABJB010197286; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010374606; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010714685; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB011121280; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS749327; EEC07950.1; -; Genomic_DNA.
DR RefSeq; XP_002435126.1; XM_002435081.1.
DR AlphaFoldDB; B7PMX8; -.
DR STRING; 6945.B7PMX8; -.
DR PaxDb; 6945-B7PMX8; -.
DR EnsemblMetazoa; ISCW005633-RA; ISCW005633-PA; ISCW005633.
DR KEGG; isc:IscW_ISCW005633; -.
DR VEuPathDB; VectorBase:ISCI005633; -.
DR VEuPathDB; VectorBase:ISCP_018694; -.
DR VEuPathDB; VectorBase:ISCW005633; -.
DR HOGENOM; CLU_002472_8_5_1; -.
DR InParanoid; B7PMX8; -.
DR OMA; CIPNIAD; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361:SF148; DNA MISMATCH REPAIR PROTEIN MSH6; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR SMART; SM00534; MUTSac; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 1: Evidence at protein level;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Proteomics identification {ECO:0007829|PeptideAtlas:B7PMX8};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555}.
FT DOMAIN 296..312
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EEC07950.1"
FT NON_TER 401
FT /evidence="ECO:0000313|EMBL:EEC07950.1"
SQ SEQUENCE 401 AA; 44284 MW; AAE94D5C400A48DB CRC64;
HEEAKKNGKV TPSKGVDKDY DDAMRRVKAA TRELEDYLET QCRHFKCKAT YHGTGKNRFQ
IEVPESASRL AGAGYELQGQ RKGFKRYWTS RVKELAAHLV SAEEAQEAAI KDIMRRIFES
FDRRHGLPSL QEWEVAVQCL AILDCLLSLA QYSSSLTGTA CTPRILRDGE VSRTPRLSIQ
GGRHPCLLKH LGGENLIPNS IALGDYEDDD SAPRGARLAL VTGPNMGGKS TLMRQAGLLV
IIAQMGAKVP AESCELTLVD RIFTRLGASD RITSGNTFFV EVNETSAILR HATRHSLVLL
DELGRGTSTH DGMSIAHAVV KELSTKIHCR TLFSTHYHHL VEGFTSDPNV YLGHMACMVE
NENEDDPTQE TIVFLYKFAR GACPKSYGFN AAKLAGIPPD V
//
