ID B7PUZ3_IXOSC Unreviewed; 207 AA.
AC B7PUZ3;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 24-JAN-2024, entry version 64.
DE RecName: Full=BLOC-1-related complex subunit 5 {ECO:0000256|ARBA:ARBA00022300};
GN ORFNames=IscW_ISCW007138 {ECO:0000313|EMBL:EEC10415.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC10415.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC10415.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW007138-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW007138-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Lysosome membrane
CC {ECO:0000256|ARBA:ARBA00004122}; Lipid-anchor
CC {ECO:0000256|ARBA:ARBA00004122}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004122}.
CC -!- SIMILARITY: Belongs to the BORCS5 family.
CC {ECO:0000256|ARBA:ARBA00010235}.
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DR EMBL; ABJB010016801; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010156274; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010542730; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010702052; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS796218; EEC10415.1; -; Genomic_DNA.
DR RefSeq; XP_002406986.1; XM_002406942.1.
DR AlphaFoldDB; B7PUZ3; -.
DR STRING; 6945.B7PUZ3; -.
DR PaxDb; 6945-B7PUZ3; -.
DR EnsemblMetazoa; ISCW007138-RA; ISCW007138-PA; ISCW007138.
DR KEGG; isc:IscW_ISCW007138; -.
DR VEuPathDB; VectorBase:ISCP_027206; -.
DR VEuPathDB; VectorBase:ISCW007138; -.
DR HOGENOM; CLU_064176_1_0_1; -.
DR InParanoid; B7PUZ3; -.
DR OMA; CLRYQEH; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0099078; C:BORC complex; IBA:GO_Central.
DR GO; GO:0098574; C:cytoplasmic side of lysosomal membrane; IBA:GO_Central.
DR GO; GO:0030672; C:synaptic vesicle membrane; IBA:GO_Central.
DR GO; GO:0032418; P:lysosome localization; IBA:GO_Central.
DR GO; GO:0072384; P:organelle transport along microtubule; IBA:GO_Central.
DR GO; GO:1903744; P:positive regulation of anterograde synaptic vesicle transport; IBA:GO_Central.
DR CDD; cd22789; BORCS5-like; 1.
DR InterPro; IPR018780; TBORCS5.
DR PANTHER; PTHR31634; BLOC-1-RELATED COMPLEX SUBUNIT 5; 1.
DR PANTHER; PTHR31634:SF2; BLOC-1-RELATED COMPLEX SUBUNIT 5; 1.
DR Pfam; PF10158; LOH1CR12; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|PeptideAtlas:B7PUZ3};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555}.
FT REGION 14..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 207 AA; 23124 MW; CED618EB8EFA7570 CRC64;
MGLYSYLVRG AVPESPKLSS KSPAHLLRNS PRPSPKPRPH SYAGTSGHDI VVVKEGSLDI
QTVDTDEDLL KLQAIPQFLP ILRGSLHSPI ICDADVADKL DHRAVNRLAS RYQDHLRQCA
EVVSTEQNAL ASRIREMDYA VSTLSNMLTE RQKKFAKYVE QLSRVHELSG MLQTSQTLLT
KTIEQLDTLN KLLPPDEQLE PFIMVTG
//
