ID B7Q6S4_IXOSC Unreviewed; 240 AA.
AC B7Q6S4;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 24-JAN-2024, entry version 59.
DE SubName: Full=Prostate-specific transglutaminase, putative {ECO:0000313|EMBL:EEC14546.1, ECO:0000313|EnsemblMetazoa:ISCW011739-PA};
DE EC=2.3.2.13 {ECO:0000313|EMBL:EEC14546.1};
GN ORFNames=IscW_ISCW011739 {ECO:0000313|EMBL:EEC14546.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC14546.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC14546.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW011739-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW011739-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the transglutaminase superfamily.
CC Transglutaminase family. {ECO:0000256|ARBA:ARBA00005968}.
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DR EMBL; ABJB010110829; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010655687; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS869931; EEC14546.1; -; Genomic_DNA.
DR RefSeq; XP_002412027.1; XM_002411982.1.
DR AlphaFoldDB; B7Q6S4; -.
DR PaxDb; 6945-B7Q6S4; -.
DR EnsemblMetazoa; ISCW011739-RA; ISCW011739-PA; ISCW011739.
DR KEGG; isc:IscW_ISCW011739; -.
DR VEuPathDB; VectorBase:ISCI011739; -.
DR VEuPathDB; VectorBase:ISCP_027089; -.
DR VEuPathDB; VectorBase:ISCW011739; -.
DR HOGENOM; CLU_1157532_0_0_1; -.
DR InParanoid; B7Q6S4; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0003810; F:protein-glutamine gamma-glutamyltransferase activity; IEA:UniProtKB-EC.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR001102; Transglutaminase_N.
DR PANTHER; PTHR11590:SF40; HEMOCYTE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE-LIKE PROTEIN; 1.
DR PANTHER; PTHR11590; PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE; 1.
DR Pfam; PF00868; Transglut_N; 1.
DR SUPFAM; SSF81296; E set domains; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000313|EMBL:EEC14546.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Transferase {ECO:0000313|EMBL:EEC14546.1}.
FT DOMAIN 56..180
FT /note="Transglutaminase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00868"
SQ SEQUENCE 240 AA; 26714 MW; ACB3BA4C587BE73E CRC64;
MEEGEGRETM TSSTTLKPLL DFASGNPSAD DLDKVALVVG FMREPEPVTG RAAVISVDMF
EKKNAKDNFT TFYKQVYGQF PSCVLRRGSR FHLGIRFNQE VELHNLDVKV NFALGVNPTI
KDGTLVKLQL PTLVDDKGTA QVKLSQWSIS VTFHQKDTVL LMLRTPATTP VGRWTLGFQV
GAALQTIDRK IYVVCNPWLQ GRLRFSGQSG IRTPIYELPG IRSFRGVGAF DDRTKCLSGR
//
