ID B7QDI1_IXOSC Unreviewed; 203 AA.
AC B7QDI1;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Cytochrome P-450 IIC5, putative {ECO:0000313|EMBL:EEC16903.1, ECO:0000313|EnsemblMetazoa:ISCW012594-PA};
DE EC=1.14.14.1 {ECO:0000313|EMBL:EEC16903.1};
GN ORFNames=IscW_ISCW012594 {ECO:0000313|EMBL:EEC16903.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC16903.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC16903.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW012594-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW012594-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971};
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|ARBA:ARBA00010617, ECO:0000256|RuleBase:RU000461}.
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DR EMBL; ABJB010075963; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010351943; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010615967; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS913843; EEC16903.1; -; Genomic_DNA.
DR RefSeq; XP_002413595.1; XM_002413550.1.
DR AlphaFoldDB; B7QDI1; -.
DR PaxDb; 6945-B7QDI1; -.
DR EnsemblMetazoa; ISCW012594-RA; ISCW012594-PA; ISCW012594.
DR KEGG; isc:IscW_ISCW012594; -.
DR VEuPathDB; VectorBase:ISCI012594; -.
DR VEuPathDB; VectorBase:ISCP_020418; -.
DR VEuPathDB; VectorBase:ISCW012594; -.
DR HOGENOM; CLU_001570_22_2_1; -.
DR InParanoid; B7QDI1; -.
DR OMA; ITHREPV; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0070330; F:aromatase activity; IEA:UniProtKB-EC.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR017972; Cyt_P450_CS.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR24300:SF281; CYTOCHROME P450 2U1; 1.
DR PANTHER; PTHR24300; CYTOCHROME P450 508A4-RELATED; 1.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
DR PROSITE; PS00086; CYTOCHROME_P450; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|RuleBase:RU000461}; Iron {ECO:0000256|RuleBase:RU000461};
KW Metal-binding {ECO:0000256|RuleBase:RU000461};
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033,
KW ECO:0000256|RuleBase:RU000461};
KW Oxidoreductase {ECO:0000256|RuleBase:RU000461,
KW ECO:0000313|EMBL:EEC16903.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555}.
SQ SEQUENCE 203 AA; 23211 MW; 0B272DA2AA4081CB CRC64;
MLDFFVAGTA SSAATISCII YHCANQPDTL QAKIYGEIDR VVGSCNTPTW EDHQAMLLYT
MAVIWEMQRW KTLNPFNLPR LAEEDVSLNG YRIPKGTVVL ANFWAVHFDP KYWKNPEEFD
PYRFLTHDES ALLSKPEYLL TFSIGKRMCP GELLATVDVF LCVTTLLQKF RVLPEEGTSF
SVATDHYTDL LAKRLCFLSR LPE
//
