ID B7QH38_IXOSC Unreviewed; 805 AA.
AC B7QH38;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 96.
DE SubName: Full=Myb transforming protein, putative {ECO:0000313|EMBL:EEC18160.1, ECO:0000313|EnsemblMetazoa:ISCW023285-PA};
GN ORFNames=IscW_ISCW023285 {ECO:0000313|EMBL:EEC18160.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC18160.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC18160.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW023285-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW023285-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the CEF1 family.
CC {ECO:0000256|ARBA:ARBA00010506}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ABJB010203091; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010305387; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010594618; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010891096; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB011069076; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS936446; EEC18160.1; -; Genomic_DNA.
DR RefSeq; XP_002414495.1; XM_002414450.1.
DR AlphaFoldDB; B7QH38; -.
DR STRING; 6945.B7QH38; -.
DR PaxDb; 6945-B7QH38; -.
DR EnsemblMetazoa; ISCW023285-RA; ISCW023285-PA; ISCW023285.
DR KEGG; isc:IscW_ISCW023285; -.
DR VEuPathDB; VectorBase:ISCI023285; -.
DR VEuPathDB; VectorBase:ISCP_002485; -.
DR VEuPathDB; VectorBase:ISCW023285; -.
DR HOGENOM; CLU_009082_0_0_1; -.
DR InParanoid; B7QH38; -.
DR OMA; KMGMAGE; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0000974; C:Prp19 complex; IBA:GO_Central.
DR GO; GO:0005681; C:spliceosomal complex; IBA:GO_Central.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd00167; SANT; 1.
DR CDD; cd11659; SANT_CDC5_II; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR InterPro; IPR047242; CDC5L/Cef1.
DR InterPro; IPR021786; Cdc5p/Cef1_C.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR001005; SANT/Myb.
DR InterPro; IPR047240; SANT_CDC5L_II.
DR PANTHER; PTHR45885; CELL DIVISION CYCLE 5-LIKE PROTEIN; 1.
DR PANTHER; PTHR45885:SF1; CELL DIVISION CYCLE 5-LIKE PROTEIN; 1.
DR Pfam; PF11831; Myb_Cef; 1.
DR Pfam; PF00249; Myb_DNA-binding; 2.
DR SMART; SM00717; SANT; 2.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS51294; HTH_MYB; 2.
DR PROSITE; PS50090; MYB_LIKE; 2.
PE 1: Evidence at protein level;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Proteomics identification {ECO:0007829|PeptideAtlas:B7QH38};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
FT DOMAIN 1..58
FT /note="HTH myb-type"
FT /evidence="ECO:0000259|PROSITE:PS51294"
FT DOMAIN 3..54
FT /note="Myb-like"
FT /evidence="ECO:0000259|PROSITE:PS50090"
FT DOMAIN 55..104
FT /note="Myb-like"
FT /evidence="ECO:0000259|PROSITE:PS50090"
FT DOMAIN 59..108
FT /note="HTH myb-type"
FT /evidence="ECO:0000259|PROSITE:PS51294"
FT REGION 111..145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 189..355
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 395..444
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 733..799
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 189..273
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 316..330
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 428..444
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 805 AA; 91559 MW; B740E51204091319 CRC64;
MPRIMIKGGV WRNTEDEILK AAVMKYGKNQ WSRIASLLHR KSAKQCKARW YEWLDPSIKK
TEWAREEEEK LLHLAKLMPT QWRTIAPIIG RTAAQCLEHY EYLLDQAQKK EEDGEILDDP
RKLKPGEIDP NPETKPARPD PKDMDEDELE MLSEARARLA NTQGKKAKRK AREKQLEEAR
RLAALQKRRE LRMAGISLPP RRRKRHAIDY NKEIPFEKRP APGLHDTSDE VYDPTETDFR
RLRQQHLEGE LRSEKEERER RKDKQKLKQR KENDLPPALL SGSSEPARKR SKLVLPEPQI
SESELEQVVK LGKASETARE AAEESGHKAS EPLLADYSLT PGGAGPLRTP KGPSLSRDTI
LMEAQNIMAL TNVDTPLKGG LNTPLHETEI GVATPKKAGT MTPNNLIVTP FRTPGGTLEG
TTPRGGRTPG SIPGSTPLSS ATPLRDKLNI NPEDHLDFDT NQSAKQFQKQ TKQHLLKALS
SLPAPKNDYE IVVPEDDPSL LESASQEHMV EDQADMDSAK EHERLEKLEA ERKLQSLAVQ
RDLPRPLDVN ASVLRPAHTE PPLTDLQRAE ELIKQEMLVM QHYDALHHPT AHQRPGGGPR
KGAPMDEAQH LAYLDRHPYR KYSREDLQAA EEVLKAEMEV VRRGMGHGDL SLEAYSQVWD
ECLAQVLFLP AQNRYTRANL ASKKDRIESL DKRLEQNRGH MTREAKKAAK VEKKLRVLLG
GYQAIPIALI KQIQELAEQI EQTHLELKTF QALQEHESLA IPKRVEALTE DVNRQVEREK
ALQKRYNDLL QQKELVEEAL VDVQS
//
