ID B7QHR8_IXOSC Unreviewed; 312 AA.
AC B7QHR8;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Zinc/iron transporter, putative {ECO:0000313|EMBL:EEC18390.1, ECO:0000313|EnsemblMetazoa:ISCW014525-PA};
DE EC=1.3.1.74 {ECO:0000313|EMBL:EEC18390.1};
GN ORFNames=IscW_ISCW014525 {ECO:0000313|EMBL:EEC18390.1};
OS Ixodes scapularis (Black-legged tick) (Deer tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=6945;
RN [1] {ECO:0000313|EMBL:EEC18390.1, ECO:0000313|Proteomes:UP000001555}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wikel {ECO:0000313|Proteomes:UP000001555}, and Wikel colony
RC {ECO:0000313|EMBL:EEC18390.1};
RG Ixodes scapularis Genome Project Consortium;
RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., Amedeo P.,
RA Galinsky K.J., Schobel S., Inman J., Hostetler J., Miller J., Hammond M.,
RA Megy K., Lawson D., Kodira C., Sutton G., Meyer J., Hill C.A., Birren B.,
RA Nene V., Collins F., Alarcon-Chaidez F., Wikel S., Strausberg R.;
RT "Annotation of Ixodes scapularis.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EnsemblMetazoa:ISCW014525-PA}
RP IDENTIFICATION.
RC STRAIN=wikel {ECO:0000313|EnsemblMetazoa:ISCW014525-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; ABJB010804626; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010824840; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ABJB010884944; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; DS941486; EEC18390.1; -; Genomic_DNA.
DR RefSeq; XP_002414725.1; XM_002414680.1.
DR AlphaFoldDB; B7QHR8; -.
DR STRING; 6945.B7QHR8; -.
DR PaxDb; 6945-B7QHR8; -.
DR EnsemblMetazoa; ISCW014525-RA; ISCW014525-PA; ISCW014525.
DR KEGG; isc:IscW_ISCW014525; -.
DR VEuPathDB; VectorBase:ISCI014525; -.
DR VEuPathDB; VectorBase:ISCP_019125; -.
DR VEuPathDB; VectorBase:ISCW014525; -.
DR HOGENOM; CLU_040462_0_1_1; -.
DR InParanoid; B7QHR8; -.
DR OMA; FHWTKAS; -.
DR OrthoDB; 1121097at2759; -.
DR Proteomes; UP000001555; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0032440; F:2-alkenal reductase [NAD(P)+] activity; IEA:UniProtKB-EC.
DR GO; GO:0005385; F:zinc ion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0071577; P:zinc ion transmembrane transport; IBA:GO_Central.
DR InterPro; IPR003689; ZIP.
DR PANTHER; PTHR11040:SF203; FI18611P1-RELATED; 1.
DR PANTHER; PTHR11040; ZINC/IRON TRANSPORTER; 1.
DR Pfam; PF02535; Zip; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000313|EMBL:EEC18390.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001555};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 41..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 75..93
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 167..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 194..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 227..249
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 255..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 289..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 119..159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 131..155
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 312 AA; 33972 MW; B88E3D56E73B34B4 CRC64;
MAVQVAQIVA PLLLLFGTIF LGVLPIWLVR RVSAIQRGAQ VLAFLVCLGG GVLFATTFLH
LIPEVREGFE KLNKDFPVAE GVICLGFLAV YALEELIHAW LGDDHSVAGH GLAHSPALVE
SRHERENSNQ GGLQEHQGNR ETTQEPETET CPTTTDDEAP LHEATTAGIL IVAALSFHSL
FEGLSLGLQD SERATWIMFL AISFHKYVLA FVVGFDISAS RVRPRNVVIQ MLVFSVMSPL
GALVGAITRN NLEDTIVVVV LNGIASGTLI YITFFEVLQR QKNDTLSGLC RLLAVIVGFT
LMLTLILVLP HD
//
