ID B7R1N6_9EURY Unreviewed; 378 AA.
AC B7R1N6;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE SubName: Full=NADPH-dependent butanol dehydrogenase {ECO:0000313|EMBL:EEB74113.1};
GN ORFNames=TAM4_1480 {ECO:0000313|EMBL:EEB74113.1};
OS Thermococcus sp. AM4.
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Thermococcus.
OX NCBI_TaxID=246969 {ECO:0000313|EMBL:EEB74113.1, ECO:0000313|Proteomes:UP000009277};
RN [1] {ECO:0000313|EMBL:EEB74113.1, ECO:0000313|Proteomes:UP000009277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AM4 {ECO:0000313|EMBL:EEB74113.1,
RC ECO:0000313|Proteomes:UP000009277};
RX PubMed=22123768; DOI=10.1128/JB.06259-11;
RA Oger P., Sokolova T.G., Kozhevnikova D.A., Chernyh N.A., Bartlett D.H.,
RA Bonch-Osmolovskaya E.A., Lebedinsky A.V.;
RT "Complete Genome Sequence of the Hyperthermophilic Archaeon Thermococcus
RT sp. Strain AM4, Capable of Organotrophic Growth and Growth at the Expense
RT of Hydrogenogenic or Sulfidogenic Oxidation of Carbon Monoxide.";
RL J. Bacteriol. 193:7019-7020(2011).
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DR EMBL; CP002952; EEB74113.1; -; Genomic_DNA.
DR RefSeq; WP_014122106.1; NC_016051.1.
DR AlphaFoldDB; B7R1N6; -.
DR STRING; 246969.TAM4_1480; -.
DR GeneID; 7418789; -.
DR KEGG; tha:TAM4_1480; -.
DR eggNOG; arCOG00984; Archaea.
DR HOGENOM; CLU_007207_0_0_2; -.
DR OrthoDB; 57329at2157; -.
DR Proteomes; UP000009277; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd08179; NADPH_BDH; 1.
DR Gene3D; 3.40.50.1970; -; 1.
DR Gene3D; 1.20.1090.10; Dehydroquinate synthase-like - alpha domain; 1.
DR InterPro; IPR001670; ADH_Fe/GldA.
DR InterPro; IPR039697; Alcohol_dehydrogenase_Fe.
DR InterPro; IPR034802; NADPH_BDH.
DR PANTHER; PTHR11496; ALCOHOL DEHYDROGENASE; 1.
DR PANTHER; PTHR11496:SF83; HYDROXYACID-OXOACID TRANSHYDROGENASE, MITOCHONDRIAL; 1.
DR Pfam; PF00465; Fe-ADH; 1.
DR SUPFAM; SSF56796; Dehydroquinate synthase-like; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 6..367
FT /note="Alcohol dehydrogenase iron-type/glycerol
FT dehydrogenase GldA"
FT /evidence="ECO:0000259|Pfam:PF00465"
SQ SEQUENCE 378 AA; 42229 MW; 5A6A8A78A6A942A8 CRC64;
MFWLKTRIIE GKGSLEKLRK EASGHEKVLI LASNSMKKHG FLREVEDYVR EAGAEVLSIA
GLPAEPSVET IEEFLPKVRE FKPDLLIALG GGSVIDTTKA LKVFYDAPEL KFEEIAFIDR
FSRPKPVPKL KTKLIAIPST SGAGSEVSGA SVLKKGGIKY NIVTPEIAPD VAILDPRLPM
TMPREVARNS GLDVLVHGIE AYTTKVANDF SDAMAIKAIK TVFSYLEKSL EGDEEARERM
HYASTMAGIA FLNARLGLCH AMSHKAAWLG PHGLLNAIFL PYVMEFNAGR SDYARRRYDE
IARELGLKDW RALVDAVREL NERTGVPKLS ELVDEETFMA RLDEMAEKAY RDGLVFFNPV
EPRPEEIREL YLKAFRGE
//
