ID   B7RYC9_9GAMM            Unreviewed;       686 AA.
AC   B7RYC9;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   SubName: Full=Vault protein inter-alpha-trypsin {ECO:0000313|EMBL:EEB78579.1};
GN   ORFNames=GPB2148_1477 {ECO:0000313|EMBL:EEB78579.1};
OS   marine gamma proteobacterium HTCC2148.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Cellvibrionales; Halieaceae.
OX   NCBI_TaxID=247634 {ECO:0000313|EMBL:EEB78579.1, ECO:0000313|Proteomes:UP000002793};
RN   [1] {ECO:0000313|Proteomes:UP000002793}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HTCC2148 {ECO:0000313|Proteomes:UP000002793};
RX   PubMed=20472793; DOI=10.1128/jb.00511-10;
RA   Thrash J.C., Cho J.C., Ferriera S., Johnson J., Vergin K.L.,
RA   Giovannoni S.J.;
RT   "Genome sequences of strains HTCC2148 and HTCC2080, belonging to the
RT   OM60/NOR5 clade of the Gammaproteobacteria.";
RL   J. Bacteriol. 192:3842-3843(2010).
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DR   EMBL; DS999227; EEB78579.1; -; Genomic_DNA.
DR   AlphaFoldDB; B7RYC9; -.
DR   STRING; 247634.GPB2148_1477; -.
DR   eggNOG; COG2304; Bacteria.
DR   HOGENOM; CLU_011139_1_1_6; -.
DR   Proteomes; UP000002793; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR022440; CHP03788.
DR   InterPro; IPR013694; VIT.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   NCBIfam; TIGR03788; marine_srt_targ; 1.
DR   PANTHER; PTHR45737; VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 5A; 1.
DR   PANTHER; PTHR45737:SF6; VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN DDB_G0286969-RELATED; 1.
DR   Pfam; PF08487; VIT; 1.
DR   Pfam; PF13768; VWA_3; 1.
DR   SMART; SM00609; VIT; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS51468; VIT; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002793};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        659..679
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          20..148
FT                   /note="VIT"
FT                   /evidence="ECO:0000259|PROSITE:PS51468"
FT   DOMAIN          317..493
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   REGION          629..649
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   686 AA;  75375 MW;  F54F40F802E089A1 CRC64;
     MILASTSAQA EDYLDDVASG QMLLREEGEA YQPAPTQSTK VDLVVTGMLA TVTVEQEFHN
     AGADWVEGVY AFPLPEDAAV RRLEMLIGER RIVGKIRERK EAKRVYQQAL KQGKKAVLVE
     QQRPNLFTNR VANIAPGEKI TVRLEYVQSV EHRSGRFSLR LPTTITPRYM PGVETETANQ
     DMNENVAVTP SHGWAWPTDQ VTDAHLISPL QYFAQGSDSA PLNRIKISAR LDMGMPLASI
     DSPYHEIALS RRAGVYSVKL AQGSAEMDRD FVLQWSAASG SLPGAAFFTE RVDDQYYGLL
     MLVPPASQRA AETVPREIVF VVDTSGSMGG VSIKQAKGSL TRALRHLGPN DRFNVIEFNS
     SHRALFQHAV PASHHNLQLA SEYVRHLEAS GGTEMMPALQ LALKLPGAQD ELRPEPALRQ
     VIFITDGAVG NESALFEHIV DSLGGSRLFT VGIGSAPNAW FMRKAAEYGR GTFTYIGDVA
     EVGEKMDALF LNLTRPVATH LNVDWPDGVD VWPARTPDLY AGEPLLIAVK LGDELPIDGL
     KIQGLLGETE WSTKLQFPAA LNPLSMNNSE GVATLWARKK IEGLIDEKYR GKSEDWVRER
     VLPLALKHSL LSPYTSFVAV EEVVSRPESE AAKSKPLPNT RPQGQSPQFF AYPNTATTAA
     ANIWLGSFLL LIALFIIAIR ERSADA
//