ID B7S739_9BURK Unreviewed; 501 AA.
AC B7S739;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN Name=aoxS {ECO:0000313|EMBL:ACJ83256.1};
GN ORFNames=KYC_14772 {ECO:0000313|EMBL:EHK65489.1};
OS Achromobacter arsenitoxydans SY8.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Achromobacter.
OX NCBI_TaxID=477184 {ECO:0000313|EMBL:ACJ83256.1};
RN [1] {ECO:0000313|EMBL:ACJ83256.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=SY8 {ECO:0000313|EMBL:ACJ83256.1};
RX PubMed=19283378; DOI=10.1007/s00253-009-1929-4;
RA Cai L., Rensing C., Li X., Wang G.;
RT "Novel gene clusters involved in arsenite oxidation and resistance in two
RT arsenite oxidizers: Achromobacter sp. SY8 and Pseudomonas sp. TS44.";
RL Appl. Microbiol. Biotechnol. 83:715-725(2009).
RN [2] {ECO:0000313|EMBL:ACJ83256.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=SY8 {ECO:0000313|EMBL:ACJ83256.1};
RX PubMed=19128515; DOI=10.1186/1471-2180-9-4;
RA Cai L., Liu G., Rensing C., Wang G.;
RT "Genes involved in arsenic transformation and resistance associated with
RT different levels of arsenic-contaminated soils.";
RL BMC Microbiol. 9:4-4(2009).
RN [3] {ECO:0000313|EMBL:EHK65489.1, ECO:0000313|Proteomes:UP000003113}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SY8 {ECO:0000313|EMBL:EHK65489.1,
RC ECO:0000313|Proteomes:UP000003113};
RX PubMed=22328747; DOI=10.1128/JB.06667-11;
RA Li X., Hu Y., Gong J., Lin Y., Johnstone L., Rensing C., Wang G.;
RT "Genome sequence of the highly efficient arsenite-oxidizing bacterium
RT Achromobacter arsenitoxydans SY8.";
RL J. Bacteriol. 194:1243-1244(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; EF523515; ACJ83256.1; -; Genomic_DNA.
DR EMBL; AGUF01000052; EHK65489.1; -; Genomic_DNA.
DR RefSeq; WP_008163536.1; NZ_AGUF01000052.1.
DR AlphaFoldDB; B7S739; -.
DR STRING; 477184.KYC_14772; -.
DR PATRIC; fig|477184.5.peg.2928; -.
DR eggNOG; COG4191; Bacteria.
DR OrthoDB; 2521613at2; -.
DR Proteomes; UP000003113; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR PANTHER; PTHR45436:SF15; SENSOR HISTIDINE KINASE CRDS; 1.
DR PANTHER; PTHR45436; SENSOR HISTIDINE KINASE YKOH; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ACJ83256.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 20..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 187..209
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 211..266
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 286..490
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 501 AA; 54809 MW; 6AC3A1D9BE5E07D0 CRC64;
MNFGRWNFWS RVSYRYKVPL ALAAAIVVTE LVVTVTLVRT AYVGMLRDTR QSAKTLTQVL
SLSVREPLVR DDLWRVYEAL RIPLAAGDGA PGLRSILVLD PNLRVYASSD PQQFPVLTPS
AALPTELRAA AETLRGDQRA FVFTSPDSLD ASLAVAGAAV MSEDDGLAGY VLAAYDAGTW
RQRLYDLVAR VLLVSIPGLL LLLTLGWLWG NRIAQPLLSL ARATQRVGRE PAANIEHSRH
KDGSDEIAAL SKSFSTMLKQ LERQEALERE IIAAERLAAV GRVAAGVAHE INNPLGGMLN
ALDTIEKHGS YDELTGKTLG LTRRGLMQIR RTVCALLVEA RLDSPLMHAS DWQDLRVLIE
PELSEKGATL LWDVTAQQEL PLPSHLVRQL TLNLLINAKN AVDLGGTVSC TVTGIQDQLT
VEVANSGQHI PDDALPHLFE PYRVDAQKGS RARGLGLWVT YQIVTQLEGT IEVVSEEGYT
AFTVTLPCAT PIQEEHQETP T
//
