ID B7SFV6_CHICK Unreviewed; 386 AA.
AC B7SFV6; F1P357;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 109.
DE SubName: Full=DLK1 {ECO:0000313|EMBL:ABZ04469.1};
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031 {ECO:0000313|EMBL:ABZ04469.1};
RN [1] {ECO:0000313|EMBL:ABZ04469.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=19038821;
RA Shin J., Lim S., Latshaw J.D., Lee K.;
RT "Cloning and expression of delta-like protein 1 messenger ribonucleic acid
RT during development of adipose and muscle tissues in chickens.";
RL Poult. Sci. 87:2636-2646(2008).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; EU288039; ABZ04469.1; -; mRNA.
DR RefSeq; NP_001135726.1; NM_001142254.1.
DR AlphaFoldDB; B7SFV6; -.
DR SMR; B7SFV6; -.
DR STRING; 9031.ENSGALP00000018320; -.
DR PaxDb; 9031-ENSGALP00000018320; -.
DR KEGG; gga:423459; -.
DR VEuPathDB; HostDB:geneid_423459; -.
DR eggNOG; KOG1217; Eukaryota.
DR HOGENOM; CLU_039179_0_1_1; -.
DR InParanoid; B7SFV6; -.
DR Bgee; ENSGALG00000011244; Expressed in brain and 3 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0045746; P:negative regulation of Notch signaling pathway; IBA:GO_Central.
DR CDD; cd00054; EGF_CA; 4.
DR Gene3D; 2.10.25.10; Laminin; 5.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR PANTHER; PTHR12916; CYTOCHROME C OXIDASE POLYPEPTIDE VIC-2; 1.
DR PANTHER; PTHR12916:SF4; NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1-RELATED; 1.
DR Pfam; PF21700; DL-JAG_EGF-like; 1.
DR Pfam; PF00008; EGF; 4.
DR SMART; SM00181; EGF; 6.
DR SMART; SM00179; EGF_CA; 4.
DR SUPFAM; SSF57196; EGF/Laminin; 4.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS00022; EGF_1; 5.
DR PROSITE; PS01186; EGF_2; 4.
DR PROSITE; PS50026; EGF_3; 5.
DR PROSITE; PS01187; EGF_CA; 1.
PE 2: Evidence at transcript level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}.
FT DOMAIN 27..60
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 93..130
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 132..173
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 175..211
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 213..250
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 50..59
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 120..129
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 163..172
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 201..210
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 240..249
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 386 AA; 41363 MW; BCF6CC7F19BB06BD CRC64;
MRLRAAGLLG CCCCCCCLLP LVLPAAPGVS CKAGCHPVNG FCEFPSECRC LPGWQGALCN
QCVPFPGCLH GSCVKPWQCI CEEGWVGSLC DIDIQPCSAK PCTNNSTCIE TGDGGYICLC
AQGFTGKNCH LRKGPCIING SPCQNGGTCI DDNGFAPHAS CLCPSGFAGN FCEIDRDDCE
SNPCENGGTC TDIGAGFSCL CPHGYTGKLC SSRVTFCASD PCENGGTCKE HPQGGFKCIC
KPEFVGATCK HASKNTSLSA VNIGTKNMQN YKIPPKAHHR SVHQEHEILK ITMKETIQNA
DLLLSKSQVI CFVVLGLLTC LVVLGTTGIV FFSKCEMWLA NAKYSHLLRK KKNFLLKSSN
GENLSVNIIF PEKIKLTNYT KNYTAI
//
