ID B7T4W6_KLEPN Unreviewed; 434 AA.
AC B7T4W6;
DT 10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT 10-FEB-2009, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=MucB {ECO:0000313|EMBL:ACJ65267.1};
GN Name=mucB {ECO:0000313|EMBL:ACJ65267.1};
OS Klebsiella pneumoniae.
OG Plasmid pCTXM360 {ECO:0000313|EMBL:ACJ65267.1}, and
OG Plasmid pNDM-OM {ECO:0000313|EMBL:AFZ84511.1}.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX NCBI_TaxID=573 {ECO:0000313|EMBL:ACJ65267.1};
RN [1] {ECO:0000313|EMBL:ACJ65267.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=0773 {ECO:0000313|EMBL:ACJ65267.1};
RC PLASMID=pCTXM360 {ECO:0000313|EMBL:ACJ65267.1};
RA Zhu W., Wang J., Zhuang X., Lu Y.;
RT "Complete Nucleotide Sequences of the pCTX-M360 and pKpn114 Plasmids in the
RT Multidrug Resistant Klebsiella pneumoniae in China: Evidence for pCTX-M360
RT as an intermediate plasmid between pCTX-M3 and pEL60.";
RL Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACJ65267.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=0773 {ECO:0000313|EMBL:ACJ65267.1};
RC PLASMID=pCTXM360 {ECO:0000313|EMBL:ACJ65267.1};
RX PubMed=19752275; DOI=10.1128/AAC.00032-09;
RA Zhu W.H., Luo L., Wang J.Y., Zhuang X.H., Zhong L., Liao K., Zeng Y.,
RA Lu Y.J.;
RT "Complete nucleotide sequence of pCTX-M360, an intermediate plasmid between
RT pEL60 and pCTX-M3, from a multidrug-resistant Klebsiella pneumoniae strain
RT isolated in China.";
RL Antimicrob. Agents Chemother. 53:5291-5293(2009).
RN [3] {ECO:0000313|EMBL:AFZ84511.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=601 {ECO:0000313|EMBL:AFZ84511.1};
RC PLASMID=pNDM-OM {ECO:0000313|EMBL:AFZ84511.1};
RX PubMed=23114767; DOI=10.1128/AAC.01086-12;
RA Bonnin R.A., Nordmann P., Carattoli A., Poirel L.;
RT "Comparative Genomics of IncL/M-Type Plasmids: Evolution by Acquisition of
RT Resistance Genes and Insertion Sequences.";
RL Antimicrob. Agents Chemother. 57:674-676(2013).
CC -!- SIMILARITY: Belongs to the DNA polymerase type-Y family.
CC {ECO:0000256|ARBA:ARBA00010945}.
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DR EMBL; EU938349; ACJ65267.1; -; Genomic_DNA.
DR EMBL; JX988621; AFZ84511.1; -; Genomic_DNA.
DR RefSeq; WP_011091031.1; NZ_WMIS01000034.1.
DR RefSeq; YP_002333326.1; NC_011641.1.
DR RefSeq; YP_007195525.1; NC_019889.1.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-KW.
DR CDD; cd01700; PolY_Pol_V_umuC; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.1170.60; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.30.1490.100; DNA polymerase, Y-family, little finger domain; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR InterPro; IPR025188; DUF4113.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR11076; DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; 1.
DR PANTHER; PTHR11076:SF34; PROTEIN UMUC; 1.
DR Pfam; PF13438; DUF4113; 1.
DR Pfam; PF00817; IMS; 1.
DR Pfam; PF11799; IMS_C; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50173; UMUC; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00023199};
KW Plasmid {ECO:0000313|EMBL:ACJ65267.1};
KW SOS mutagenesis {ECO:0000256|ARBA:ARBA00023199};
KW SOS response {ECO:0000256|ARBA:ARBA00023236}.
FT DOMAIN 15..200
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
SQ SEQUENCE 434 AA; 47648 MW; 84578196FE9A88EF CRC64;
MGCGYVHCYE SPPVYALIDV NSMYCSCEEA FRPDLRGRPV VVLSNNDGAL VAVNRAAKAL
GVRRGEPYFR CRRLLEQHNV AVFSSNYTLY ASFSARFATV VESLAPRTFV YSIDELFADA
SHMEGVMSPQ AFGQLLRAEV LRQTTLTCGV GVAPTKTLAK LCNHAAKTWP ATGGVVALSD
PVRLKRLMSL VSAGDVWGVG HRTEKGLATM GIKTALALAE MDIRLARRLY GVTLERTIRE
LRGEACFALE EGTGAKQQLV VSRSFGSRVT QLAQMQQAVT KYATRAGEKL RQENRLAKVV
TVFIRSSAYD AGGVPYSNQA TEVLSVPSQD TRDIIAAAQL GLSRIWREGV RYAKAGVMLS
DLQGHETQLD LFAPAAVRPG SEKLMATIDK INREGRSRVF FAGEGIDPEY AMRREMLSPA
YTTQWKDIPA AFMR
//
