ID B8BU60_THAPS Unreviewed; 888 AA.
AC B8BU60;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 08-NOV-2023, entry version 53.
DE RecName: Full=Calcineurin-like phosphoesterase domain-containing protein {ECO:0000259|Pfam:PF00149};
GN ORFNames=THAPSDRAFT_21245 {ECO:0000313|EMBL:EED95225.1};
OS Thalassiosira pseudonana (Marine diatom) (Cyclotella nana).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC Coscinodiscophyceae; Thalassiosirophycidae; Thalassiosirales;
OC Thalassiosiraceae; Thalassiosira.
OX NCBI_TaxID=35128 {ECO:0000313|EMBL:EED95225.1, ECO:0000313|Proteomes:UP000001449};
RN [1] {ECO:0000313|EMBL:EED95225.1, ECO:0000313|Proteomes:UP000001449}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1335 {ECO:0000313|EMBL:EED95225.1};
RX PubMed=15459382; DOI=10.1126/science.1101156;
RA Armbrust E.V., Berges J.A., Bowler C., Green B.R., Martinez D.,
RA Putnam N.H., Zhou S., Allen A.E., Apt K.E., Bechner M., Brzezinski M.A.,
RA Chaal B.K., Chiovitti A., Davis A.K., Demarest M.S., Detter J.C.,
RA Glavina T., Goodstein D., Hadi M.Z., Hellsten U., Hildebrand M.,
RA Jenkins B.D., Jurka J., Kapitonov V.V., Kroger N., Lau W.W., Lane T.W.,
RA Larimer F.W., Lippmeier J.C., Lucas S., Medina M., Montsant A., Obornik M.,
RA Parker M.S., Palenik B., Pazour G.J., Richardson P.M., Rynearson T.A.,
RA Saito M.A., Schwartz D.C., Thamatrakoln K., Valentin K., Vardi A.,
RA Wilkerson F.P., Rokhsar D.S.;
RT "The genome of the diatom Thalassiosira pseudonana: ecology, evolution, and
RT metabolism.";
RL Science 306:79-86(2004).
RN [2] {ECO:0000313|EMBL:EED95225.1, ECO:0000313|Proteomes:UP000001449}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1335 {ECO:0000313|EMBL:EED95225.1};
RX PubMed=18923393; DOI=10.1038/nature07410;
RA Bowler C., Allen A.E., Badger J.H., Grimwood J., Jabbari K., Kuo A.,
RA Maheswari U., Martens C., Maumus F., Otillar R.P., Rayko E., Salamov A.,
RA Vandepoele K., Beszteri B., Gruber A., Heijde M., Katinka M., Mock T.,
RA Valentin K., Verret F., Berges J.A., Brownlee C., Cadoret J.P.,
RA Chiovitti A., Choi C.J., Coesel S., De Martino A., Detter J.C., Durkin C.,
RA Falciatore A., Fournet J., Haruta M., Huysman M.J., Jenkins B.D.,
RA Jiroutova K., Jorgensen R.E., Joubert Y., Kaplan A., Kroger N., Kroth P.G.,
RA La Roche J., Lindquist E., Lommer M., Martin-Jezequel V., Lopez P.J.,
RA Lucas S., Mangogna M., McGinnis K., Medlin L.K., Montsant A.,
RA Oudot-Le Secq M.P., Napoli C., Obornik M., Parker M.S., Petit J.L.,
RA Porcel B.M., Poulsen N., Robison M., Rychlewski L., Rynearson T.A.,
RA Schmutz J., Shapiro H., Siaut M., Stanley M., Sussman M.R., Taylor A.R.,
RA Vardi A., von Dassow P., Vyverman W., Willis A., Wyrwicz L.S.,
RA Rokhsar D.S., Weissenbach J., Armbrust E.V., Green B.R., Van de Peer Y.,
RA Grigoriev I.V.;
RT "The Phaeodactylum genome reveals the evolutionary history of diatom
RT genomes.";
RL Nature 456:239-244(2008).
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DR EMBL; CM000639; EED95225.1; -; Genomic_DNA.
DR RefSeq; XP_002287782.1; XM_002287746.1.
DR AlphaFoldDB; B8BU60; -.
DR PaxDb; 35128-Thaps21245; -.
DR EnsemblProtists; EED95225; EED95225; THAPSDRAFT_21245.
DR GeneID; 7450226; -.
DR KEGG; tps:THAPSDRAFT_21245; -.
DR eggNOG; ENOG502SSXA; Eukaryota.
DR HOGENOM; CLU_325052_0_0_1; -.
DR InParanoid; B8BU60; -.
DR OMA; EPYSRRM; -.
DR Proteomes; UP000001449; Chromosome 2.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR Gene3D; 3.60.21.10; -; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR PANTHER; PTHR12905:SF0; METALLOPHOS DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12905; METALLOPHOSPHOESTERASE; 1.
DR Pfam; PF00149; Metallophos; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001449};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..888
FT /note="Calcineurin-like phosphoesterase domain-containing
FT protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002868647"
FT DOMAIN 577..765
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
FT REGION 63..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 282..304
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 321..369
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 459..499
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 843..888
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 69..90
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 326..349
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 459..480
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 888 AA; 97559 MW; F937AF708ED22684 CRC64;
MYTLSSIVTL LVLLGVSSIS AFTSPTSTKT LMYYNRVHNQ PNNAKLIPPT VLFGRSKTSG
RKIPKMPTLP VSQSVTTSPE ISPSDSNSLT STSTMVVMDV ENIRGATSFR ISHEAMLSRI
RLWREDRLSM ASGGSSGAPF LEPLLWICDH GEVPSIHHFS LFPTNHGAST TQMPHNFGVA
FAGPGRTADD VIVDLVELRC GGEELYETQP SSRNTTIVIT ADARLISRCQ QARRESSSLS
DVIFVEPASL LQQLEVYRIN SHEEESLFGE IAESEPLVVP RVTKSDVGGG SGQRRNDGKT
NSLTSFKDSS IAAEQHAKFQ ARFQKGKGSD ASTDQPQQMQ QQNNNFNNEA GDDDNEEEPG
QDASPVVDSK AASIAAQLKT EQIRRQLLLS DAFYLARPSK SRGRRSHTTM AAIHAKYKDR
NISKKQQQKL YAKRFGNQRK EGQMEAAVKR KELAEKLQRN LDRVSEENNR KERDETGYAE
SDVADSVAWS PSKSERGYGS LSNKLLGWIE EEREMSCQGS THLFDYTDIT KSDSSESSGI
LGWNAGTVGS DDKFDQLGSV LSVPLREQSA STLPPLRMVV ISDTHGFEGG LSKFSTDNQH
NDDFLLPQAD ILLHCGDFAA SGSRKTQRQA ARRLDEFLAR QTHIPEKIVV KGNHDPESPA
KVLFPDSKAL YVRASSTLVV NGVTFALEPY SRRMSLRSLR RRASASSMYA PSPLPSCDVL
VSHEPPKGVL DSTYHGISAG SSFLREQVEH AEEKPRLWLC GHIHEGRGTL TRTFKPDVCG
KEAAEGKAAA AADSTMVINC SNANSGRANR LVSGAVVVDV ERNPGEETAR STLQLRAEDD
DDLMDGANGA LPGMDNLELR ITRPGVRRRK GVPQSVRQQR LQQSRSNQ
//
