ID B8CYS8_HALOH Unreviewed; 487 AA.
AC B8CYS8;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Nucleoside-diphosphate sugar epimerase {ECO:0000313|EMBL:ACL70447.1};
GN OrderedLocusNames=Hore_16980 {ECO:0000313|EMBL:ACL70447.1};
OS Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562).
OC Bacteria; Bacillota; Clostridia; Halanaerobiales; Halothermotrichaceae;
OC Halothermothrix.
OX NCBI_TaxID=373903 {ECO:0000313|EMBL:ACL70447.1, ECO:0000313|Proteomes:UP000000719};
RN [1] {ECO:0000313|EMBL:ACL70447.1, ECO:0000313|Proteomes:UP000000719}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H 168 / OCM 544 / DSM 9562 {ECO:0000313|Proteomes:UP000000719};
RX PubMed=19145256; DOI=10.1371/journal.pone.0004192;
RA Mavromatis K., Ivanova N., Anderson I., Lykidis A., Hooper S.D., Sun H.,
RA Kunin V., Lapidus A., Hugenholtz P., Patel B., Kyrpides N.C.;
RT "Genome analysis of the anaerobic thermohalophilic bacterium
RT Halothermothrix orenii.";
RL PLoS ONE 4:E4192-E4192(2009).
CC -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC {ECO:0000256|ARBA:ARBA00007430}.
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DR EMBL; CP001098; ACL70447.1; -; Genomic_DNA.
DR RefSeq; WP_015923417.1; NC_011899.1.
DR AlphaFoldDB; B8CYS8; -.
DR STRING; 373903.Hore_16980; -.
DR KEGG; hor:Hore_16980; -.
DR eggNOG; COG1086; Bacteria.
DR HOGENOM; CLU_013560_5_2_9; -.
DR OrthoDB; 9803111at2; -.
DR Proteomes; UP000000719; Chromosome.
DR CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR041561; PglD_N.
DR InterPro; IPR003869; Polysac_CapD-like.
DR PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR Pfam; PF17836; PglD_N; 1.
DR Pfam; PF02719; Polysacc_synt_2; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000719}.
FT DOMAIN 3..73
FT /note="PglD N-terminal"
FT /evidence="ECO:0000259|Pfam:PF17836"
FT DOMAIN 145..427
FT /note="Polysaccharide biosynthesis protein CapD-like"
FT /evidence="ECO:0000259|Pfam:PF02719"
SQ SEQUENCE 487 AA; 55603 MW; 4E13A7AF27791592 CRC64;
MKNLLIIGAG SAGKLVLEEI LKNNESYNYN IIGFLDADIN KHGTSIHGYK VLGHHDNISF
YIDQYSVDEV IVATTEIDRA GLEKIYQNTK KFQIGIKVLP TLQELLMEEP FTKQLREVRV
EDLLGREPVK INSDNIYKYI NHKKVLVTGA AGSIGSELCR QIAKYDPREL IILDINENEL
YFLNLFLKRH YNLNVSLEIC NIREKSKLEY LFNYYKPQLV FHAAAHKHVP LMEKNIDEAI
KNNVFGTKNL LDLSDKYGVE KFVLISTDKA VNPTNVMGAT KRLSEIMLEK INKYSKTQYM
AVRFGNVLGS NGSVVPLFKT LIKEGKDLTV THEEATRYFM TIPEAVQLVL EAGFIGKGGE
VFVLDMGEPV KIIDLAKKMI ELSGLTLGRD INIKITGLRP GEKLHEELMH DINSCEKTQN
KKIYIAKIRE ENVDIEKGLQ DLKRYLMSFD RKKLVKKLKE LVPTYKDNSY SEENIDGRQT
KYSVIST
//
