ID B8ECW6_SHEB2 Unreviewed; 381 AA.
AC B8ECW6;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Efflux transporter, RND family, MFP subunit {ECO:0000313|EMBL:ACK48678.1};
DE Flags: Precursor;
GN OrderedLocusNames=Sbal223_4212 {ECO:0000313|EMBL:ACK48678.1};
OS Shewanella baltica (strain OS223).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Shewanellaceae; Shewanella.
OX NCBI_TaxID=407976 {ECO:0000313|EMBL:ACK48678.1, ECO:0000313|Proteomes:UP000002507};
RN [1] {ECO:0000313|Proteomes:UP000002507}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OS223 {ECO:0000313|Proteomes:UP000002507};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Chertkov O., Meincke L., Brettin T.,
RA Detter J.C., Han C., Kuske C.R., Larimer F., Land M., Hauser L.,
RA Kyrpides N., Ovchinnikova G., Brettar I., Rodrigues J., Konstantinidis K.,
RA Tiedje J.;
RT "Complete sequence of chromosome of Shewanella baltica OS223.";
RL Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004519}; Lipid-anchor
CC {ECO:0000256|ARBA:ARBA00004519}. Membrane
CC {ECO:0000256|ARBA:ARBA00004635}; Lipid-anchor
CC {ECO:0000256|ARBA:ARBA00004635}.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; CP001252; ACK48678.1; -; Genomic_DNA.
DR RefSeq; WP_012090603.1; NC_011663.1.
DR AlphaFoldDB; B8ECW6; -.
DR KEGG; sbp:Sbal223_4212; -.
DR HOGENOM; CLU_018816_2_1_6; -.
DR Proteomes; UP000002507; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0042221; P:response to chemical; IEA:UniProt.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR043602; CusB_dom_1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30158; ACRA/E-RELATED COMPONENT OF DRUG EFFLUX TRANSPORTER; 1.
DR PANTHER; PTHR30158:SF3; MULTIDRUG EFFLUX PUMP SUBUNIT ACRA-RELATED; 1.
DR Pfam; PF00529; CusB_dom_1; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Palmitate {ECO:0000256|ARBA:ARBA00023139};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 11..358
FT /note="Cation efflux system protein CusB"
FT /evidence="ECO:0000259|Pfam:PF00529"
FT DOMAIN 64..290
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT COILED 110..161
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 381 AA; 40432 MW; 201B69A8130FA04C CRC64;
MRQTIKLASV ISVALWMAAC SPQEEKAQAG AGPRSMEVGI LNVVAQPQVI QVELPGRSKA
FLEAEVRPQV SGIITKRSFV EGGNVKQGES LYQIDSATYK AALVSANADL ARANAGLASA
KAKAARYQQL VKTNAISKQE FDEAEAAYKE ALANVTVAEA AINTAKINLQ YTEVLAPISG
RIGKSSVTAG ALVTANQSQT LATIQQLDPI NVDIAQSSAQ LLRLKAKLQQ GKLQASENAD
VQLLLEDGTQ YSHLGKLQFA EVSVDENTGS VILRAEFPNP EGILLPGMYV RAMLNAGTDP
QAILVPQKAI TRNSKGQAVA MVVNDQGLVE LKIVTTAEVI DNQWRVTSGL AVGDKLIVEG
LQKIRPGAPV TTKVISETQA Q
//
