ID B8GBZ1_CHLAD Unreviewed; 2783 AA.
AC B8GBZ1;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=Cagg_0012 {ECO:0000313|EMBL:ACL22965.1};
OS Chloroflexus aggregans (strain MD-66 / DSM 9485).
OC Bacteria; Chloroflexota; Chloroflexia; Chloroflexales; Chloroflexineae;
OC Chloroflexaceae; Chloroflexus.
OX NCBI_TaxID=326427 {ECO:0000313|EMBL:ACL22965.1, ECO:0000313|Proteomes:UP000002508};
RN [1] {ECO:0000313|Proteomes:UP000002508}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MD-66 / DSM 9485 {ECO:0000313|Proteomes:UP000002508};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Pitluck S., Foster B., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Mikhailova N., Bryant D.A., Richardson P.;
RT "Complete sequence of Chloroflexus aggregans DSM 9485.";
RL Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP001337; ACL22965.1; -; Genomic_DNA.
DR RefSeq; WP_012615331.1; NC_011831.1.
DR STRING; 326427.Cagg_0012; -.
DR KEGG; cag:Cagg_0012; -.
DR eggNOG; COG2203; Bacteria.
DR eggNOG; COG5002; Bacteria.
DR HOGENOM; CLU_227858_0_0_0; -.
DR OrthoDB; 1931120at2; -.
DR Proteomes; UP000002508; Chromosome.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 12.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43047:SF72; OSMOSENSING HISTIDINE PROTEIN KINASE SLN1; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF01590; GAF; 5.
DR Pfam; PF13185; GAF_2; 6.
DR Pfam; PF13492; GAF_3; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF12860; PAS_7; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 12.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 12.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:ACL22965.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000313|EMBL:ACL22965.1}.
FT DOMAIN 2416..2469
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 2552..2771
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 2207..2248
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 2783 AA; 308029 MW; 5A9ABAC67A3F3985 CRC64;
MDTTVTRAPT QGWELLTQLA LHSQQPLGTT EPEALCRLIG ELLERHLGVG GRLTLLAGEH
ELVSVAWGDA PTNGYAFDLR DANHHYGRLT LAATFDSAFT NALTAQITTL LSIWQRSQLA
ERIERLRALG YTTLEHAGLG DMTAALEQLC REACSLLPAK ALALYWINFN DQTLLRAVSS
AGSTVFPSRL AIEDNEAIAE AITFQTGQHG TWQYHLSRRD IPTEWPMLVE PLSVGVELVG
LLILIDPGPD AAITILSLAR PLALLLHATL LQQHESRHAR ELFVLYENSL EIGSGLVIEE
TIARATENMA LALNADFGAV YLIDPNRPYQ AQTIAVHSEH LSGVRGFDTI PLTATLQRFM
EQSEPVLIAN TPLTAQDNPI AAHATMFGCQ SLWLTPLRSK EQVIGFLAMG YAASSYMLDQ
IERNLLQVLS AQIATTVQHR RLYDAAQQRA GELERLQEIS ESLAADLSLD ETLESTIAGV
AKLVRFSGAR ITLYDERYQT MRIAFQHGLR CQVGEEGDFL SSWIARHQRP LRIGNLSQPP
VWLGALDNAC ILILVNDMPA QSYLGMPLRS GNTLLGALEL VSTQAGAFSA EDERLLSIIA
GQSARAIANA NRFAQVDSSL RLRIEQLRAL QRIGSQLAIT LNQNEILAFV LEQALRATGA
SHGLIALRVN SSEATNGGRS MTELLHRSLT TDLDSEDGAF VIVEVIGYAP QLRTRLLGSA
IDQDVHTAQE SIVRREIAIG DYLSEDERSA LLCPNASSAL AAPIFYQGSV YGVVLLLAEQ
PHYFDHDAAE FLRALTHQAA IGIGNAQHYF ELEHMAKMLQ RRADILNDVL EIGQALRADQ
SLPSVLEQIG YSIIEALGLR TVMFCLVQPD DPNRLYLEAA AGIPLSEQAR LAEHPLALTL
ATRYLDPRFR LGRTYFVPAA EARLLEAGFD TRIFDYHPFS DERAEHEWQL NDRLCVPLYS
TNGMLLGMIF ASDTEDRQRP TARMVEPLEI FADQAAIAIE NHLLLQEARD RAEEMAALFQ
VGAAATSTTD LDILLERVYQ EIVAFLGIPD FFYIASYNAE QETIRFELFK QHGVTVPAYH
KRVTPKQGLT AKIIDEGKPL RIDDLLQAND LRNQLFLLVD EGRQVRSWIG VPLISQGAVI
GVLSLQSETA AAFSERTLRF LAALANQLAI ALENARLFAD REQQIRELNI INRIGQIIAA
TLDQRQMLRD VYEQLRHFLP LDSFVAFLYE PESGEMTLCY EVDEGVESFT EHRQPPTPGS
LTERIIQTRQ PLQFTDLSIE AAQAGFQPVR FGSERPSAAW LGVPLLIGDQ TVVGVLAVMS
YTPGIYHERE RAFLTTVASQ LALGVQNARL LERAQTQVEQ LALINRVAAK TNALTDLKAI
YQEIVNAMAT ATGVDQARMV IYDRESGYAP AVAEFVDSGL LDQLRIQLFD NPSVTWLDRE
KRPLVSEDAQ NDPLFAPSHE IFRALDIRSI GIIPIILNDE VIGAVGLDFV GRTGTFSPQV
LELCQTLANQ TSTAIARARA TAEAQRSAEA TRQKVSELST LLDAARILSS LLRPQEVLNK
LMELVSRQFN VTTVALWTIS EGNVLTPAAL DGIPSEQGRR MRVPIGQGFT GRVAETGQPL
IIEDVNEEGG SLYPNYQQRN NLISFMGVPV IYREQIIGVL SVMTNYRRRF TNDEMVLLSG
LANQAATALE NARLFEERER RINELTIINR ISAEVNASLD VIELIERLHA GIGEIIDTST
SLIALYDEAT NTISYPIAYD RGQRVTLESQ PLGYGTNGWV IRNRRPLLLG TASAARAMGL
LIDEGRIGDT SAIEESYLVV PIIYGNQVLG VINIQSYTQH AFDENDLRFV MTVTNQAAVA
LNNARLFAET RQNANEMSTL FEVSQSLSGT LEPDTIQMLI ADAAVRLLRA ELGAVLRLDR
RGNIERQILI DGLEFREDIR IDFRRDGLTT ALLRRDQPIA ISDLAEFDGG DHHALKLGVR
SALGIAVGPI EERLAVIWVG MRTPFEWTQH QISLLSILAN QAAQALKSAQ LFAVEQKRRR
QADMLREIAQ SFTSTLALRE IQTLVLEQLQ QIVPYDSAAM LLRDEGYGDL RVVEVRGTTC
TLPVNSTLIL ENSSLFQSMA IEHQPILIAD TYRDPRFHEL RRLGWCDGAW IGAPLLVDNE
LVGVLTVHNI EPAAYDEEAL AVVFTIASQA SQAIQNARLF DQISNLAADL DARVRERTAE
LEQATQLLSE EKERLEAVNR IALELTTQLD LDLIIQRALA LISDSLQVDR GSLMLRDVES
GALICRAVLH GRGQVQAANV PLRFANNTEG LAGWIMQHQE PVNIRDVTHD PRWVQESGRA
DTVRSVAGVP LQTGDTAIGV IILSSPQPNY FSDSQMNLLG TIASVIAAAV YNAQLYGFVN
DLALRNAVLL EEQRAESSKS AAIFRSMTEG VIVLDTTNQI TLFNPAAEQM LDIAADLVLG
QPLAHLAEVG NDDISRRRGQ TIYQGILHGL RRMRETQGIF STSIDLTDPT QVIAVNIAPV
RGLDTDYGTV AVLRDITREI EADKEKRQFI SDVSHELRTP LTAIKGYVDV LLLTASLNLT
PDQLSYLNII KNNTNRLRAL IEDILEFSRP DSKKKLTFTQ VDIPTVIEEV VQSLRLEYER
KGMKVRIDTS PSLPPVIADQ KRVSQIIFNL FSNAVKYTYE GGSITVRAFV NRANMMQIEV
EDTGVGMSPE QLKKLFRPFY RADNPLRDIA GGTGLGLSIA KQLVEMHGGE IWVTSELGKG
STFSFAIPLQ QTKSTDNDEE VEV
//
