ID B8GL85_THISH Unreviewed; 380 AA.
AC B8GL85;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Adenylate/guanylate cyclase {ECO:0000313|EMBL:ACL71603.1};
GN OrderedLocusNames=Tgr7_0506 {ECO:0000313|EMBL:ACL71603.1};
OS Thioalkalivibrio sulfidiphilus (strain HL-EbGR7).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales;
OC Ectothiorhodospiraceae; Thioalkalivibrio.
OX NCBI_TaxID=396588 {ECO:0000313|EMBL:ACL71603.1, ECO:0000313|Proteomes:UP000002383};
RN [1] {ECO:0000313|EMBL:ACL71603.1, ECO:0000313|Proteomes:UP000002383}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HL-EbGR7 {ECO:0000313|EMBL:ACL71603.1,
RC ECO:0000313|Proteomes:UP000002383};
RX PubMed=21475584;
RA Muyzer G., Sorokin D.Y., Mavromatis K., Lapidus A., Clum A., Ivanova N.,
RA Pati A., d'Haeseleer P., Woyke T., Kyrpides N.C.;
RT "Complete genome sequence of 'Thioalkalivibrio sulfidophilus' HL-EbGr7.";
RL Stand. Genomic Sci. 4:23-35(2011).
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DR EMBL; CP001339; ACL71603.1; -; Genomic_DNA.
DR RefSeq; WP_012637091.1; NC_011901.1.
DR AlphaFoldDB; B8GL85; -.
DR STRING; 396588.Tgr7_0506; -.
DR KEGG; tgr:Tgr7_0506; -.
DR eggNOG; COG0745; Bacteria.
DR eggNOG; COG2114; Bacteria.
DR HOGENOM; CLU_000445_110_0_6; -.
DR OrthoDB; 9806704at2; -.
DR Proteomes; UP000002383; Chromosome.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR CDD; cd17538; REC_D1_PleD-like; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43047:SF72; OSMOSENSING HISTIDINE PROTEIN KINASE SLN1; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR Pfam; PF00072; Response_reg; 1.
DR SMART; SM00044; CYCc; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000002383}.
FT DOMAIN 27..143
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 197..329
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
FT MOD_RES 76
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 380 AA; 42169 MW; 5BE885B13BB37DDB CRC64;
MHARQLPQGN TTTDDASLVE QAGGRRTLLV VDDQEVNRLI LARHLELLGH RVLQADSGPQ
ALQILREQSV DGVVLDVVMR GMDGYEVCRR IKADPETWFI PVVMVTVLNN QADRVRAMEA
GADEFLSKPV YPEELSARIR SLMRWRDARK ALEQARREQM RGLFSRFLCP ELVDDLLAAP
EDEARSLLKR SERRDAAVMF ADLRGFTGLS ERLSAEQVVT LLNSFFSVMT QVTHAHRGTV
FGMGGDSLLV GFGVPLPQED AGVRAFDCAR EMQRAFRGLS RSWREDWGVD AGLGIGINRG
EVVCGNVGSE SYLSYTVVGD AVNVAARLQA QARAGEVLLS GSLHETLDKE CARACESLPN
PLFLKGRSRP LPVLRWRVDC
//
