ID B8H6Q8_PSECP Unreviewed; 737 AA.
AC B8H6Q8;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=MMPL domain protein {ECO:0000313|EMBL:ACL41584.1};
GN OrderedLocusNames=Achl_3628 {ECO:0000313|EMBL:ACL41584.1};
OS Pseudarthrobacter chlorophenolicus (strain ATCC 700700 / DSM 12829 / CIP
OS 107037 / JCM 12360 / KCTC 9906 / NCIMB 13794 / A6) (Arthrobacter
OS chlorophenolicus).
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Pseudarthrobacter.
OX NCBI_TaxID=452863 {ECO:0000313|EMBL:ACL41584.1, ECO:0000313|Proteomes:UP000002505};
RN [1] {ECO:0000313|EMBL:ACL41584.1, ECO:0000313|Proteomes:UP000002505}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700700 / DSM 12829 / CIP 107037 / JCM 12360 / KCTC 9906 /
RC NCIMB 13794 / A6 {ECO:0000313|Proteomes:UP000002505};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA Goodwin L., Pitluck S., Goltsman E., Clum A., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Mikhailova N., Jansson J., Richardson P.;
RT "Complete sequence of chromosome of Arthrobacter chlorophenolicus A6.";
RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. MmpL subfamily. {ECO:0000256|ARBA:ARBA00010157}.
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DR EMBL; CP001341; ACL41584.1; -; Genomic_DNA.
DR AlphaFoldDB; B8H6Q8; -.
DR STRING; 452863.Achl_3628; -.
DR KEGG; ach:Achl_3628; -.
DR eggNOG; COG2409; Bacteria.
DR HOGENOM; CLU_005108_4_1_11; -.
DR Proteomes; UP000002505; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF6; MEMBRANE PROTEIN SCO0839-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 206..227
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 315..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 384..402
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 543..562
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 569..590
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 602..622
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 643..663
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 669..690
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 542..700
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT REGION 714..737
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 737 AA; 76951 MW; 988EBDE87C5BD1EB CRC64;
MEGIMKHQTA AKERVPFWLR WLIPVILVLT WLGLAGIGGP TFGRLEEVSS NDQASFLPAS
AEATEAQDWQ AKFRDSDEVP GIIVIENSAA FTPAQLGEVA GLRTKIEELK LGSAVIGPIP
SEDGKAVQFV APIGGSVEVK EAVKELRDTV SEGAPEGMQT YVTGPAGLAA DLTAAFGGID
GILLLVALSA VFVILLIVYR SLLLPIMVLL TSVFALCAAI LLVFGMAKAG WIQLNGQSQG
ILSILVIGAA TDYALLFVAR FREALTHTTN RTSAVITAWK ASFEPILASG ATVIIALLCL
LFSDLNSNKA LGPVAAAGIV CSLFAALTLL PALMALLGRA AFWPFRPKLV PADEREPELV
TGLEGQKGLW RATGSLVSRR PRTIWIGSVL LLVVASAGVL QLKANGVPQT DVILTASNAV
DGQDALARHF DAGSGSPAVV VADQAKAQEV LDVVKKADGV GDAYLLAQGS VPITGAPGAP
SDPDVREGKV LINATLNSAA DSLEAEEAVK ALRTDVKAVD SGALVGGVTA TALDTNTTAQ
RDLVIIIPVV LVVILFILML LLRSIVAPVL LVLSVVLSYA AAMGVSALVF NNLLGFPGAD
ATVPLFGFVF LVALGVDYNI FLMSRVREES IKHGTRPGIL RGLGVTGGVI TSAGVVLAAT
FAALGVIPIM FLVQLAFIVA FGVLLDTVLV RSLLVPALAY DLGPKIWWPG KLARGGTEPA
EKPQEPGVEP LEEVSSR
//
