ID B8HTN4_CYAP4 Unreviewed; 741 AA.
AC B8HTN4;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE SubName: Full=Capsular exopolysaccharide family {ECO:0000313|EMBL:ACL46115.1};
DE EC=2.7.10.2 {ECO:0000313|EMBL:ACL46115.1};
GN OrderedLocusNames=Cyan7425_3796 {ECO:0000313|EMBL:ACL46115.1};
OS Cyanothece sp. (strain PCC 7425 / ATCC 29141).
OC Bacteria; Cyanobacteriota; Cyanophyceae; Gomontiellales; Cyanothecaceae;
OC Cyanothece.
OX NCBI_TaxID=395961 {ECO:0000313|EMBL:ACL46115.1};
RN [1] {ECO:0000313|EMBL:ACL46115.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PCC 7425 {ECO:0000313|EMBL:ACL46115.1};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Sims D., Meineke L., Brettin T.,
RA Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Ovchinnikova G., Liberton M., Stoeckel J., Banerjee A., Singh A., Page L.,
RA Sato H., Zhao L., Sherman L., Pakrasi H., Richardson P.;
RT "Complete sequence of chromosome Cyanothece sp. PCC 7425.";
RL Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-
CC [protein]; Xref=Rhea:RHEA:10596, Rhea:RHEA-COMP:10136, Rhea:RHEA-
CC COMP:10137, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:46858,
CC ChEBI:CHEBI:82620, ChEBI:CHEBI:456216;
CC Evidence={ECO:0000256|ARBA:ARBA00001074};
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the etk/wzc family.
CC {ECO:0000256|ARBA:ARBA00008883}.
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DR EMBL; CP001344; ACL46115.1; -; Genomic_DNA.
DR AlphaFoldDB; B8HTN4; -.
DR STRING; 395961.Cyan7425_3796; -.
DR KEGG; cyn:Cyan7425_3796; -.
DR eggNOG; COG0489; Bacteria.
DR eggNOG; COG3206; Bacteria.
DR HOGENOM; CLU_009912_2_2_3; -.
DR OrthoDB; 9758283at2; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0045226; P:extracellular polysaccharide biosynthetic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd05387; BY-kinase; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR025669; AAA_dom.
DR InterPro; IPR032807; GNVR.
DR InterPro; IPR003856; LPS_length_determ_N_term.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005702; Wzc-like_C.
DR NCBIfam; TIGR01007; eps_fam; 1.
DR PANTHER; PTHR32309; TYROSINE-PROTEIN KINASE; 1.
DR PANTHER; PTHR32309:SF13; TYROSINE-PROTEIN KINASE ETK-RELATED; 1.
DR Pfam; PF13614; AAA_31; 1.
DR Pfam; PF13807; GNVR; 1.
DR Pfam; PF02706; Wzz; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ACL46115.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Tyrosine-protein kinase {ECO:0000256|ARBA:ARBA00023137}.
FT TRANSMEM 21..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 430..452
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..102
FT /note="Polysaccharide chain length determinant N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02706"
FT DOMAIN 380..451
FT /note="Tyrosine kinase G-rich"
FT /evidence="ECO:0000259|Pfam:PF13807"
FT DOMAIN 535..676
FT /note="AAA"
FT /evidence="ECO:0000259|Pfam:PF13614"
FT COILED 223..311
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 741 AA; 81729 MW; 05F0DB62A975EE4D CRC64;
MQALEDDRID LGKYLTILKR RWLGGAIAFG SILSLVIAYT LLQKPVYQAQ GLLLLKDSEN
PLASMGATSV GNLVALGGKS SPIDTEAQII RSTPIIQELI TTLQLKDPQG QLLKPEAFLE
SLSVNNIRGT DLLQVSYRST DPKQAVAIVD LLIKIYKRNN ILANRLETTN SREFIERKLP
DVTEQLRGLD RQIRSFKETH GIVDLPTEQI ESVKFKSLLA RDLAQAKSLL ATAQARATGL
SQQVGMSIDL ARFSNAVSQS KGVQVVLDQY QQVEAELAVA RTELQPDHPK IKTLEEQLTE
LNTILRERVR DVAQASRKGG SLPTSNLQTG ASEQQLVDNF INAEVERLAL SSQVTSLSRT
EQTYQQRMNA LPKLEQWLGE LERRRVVAQT IYEGLLKTLQ SLQISEQQNA GNVRLIQAAT
LSDEPVSPKL LLNLILGTIL GSLGAIVVIF ILESKDKTLK SLEEIQQYFD YVTLAMIPFD
KAAATANKAF KPTQGLERAT PQLYLRDQPN SHLSEAYRTL QANLKFLSSP DHPIRTIVIT
STRPQEGKST VSANLALAIA ELGHKVLLID ADLRLPLQHQ IWELPNATGL THLLADNHSS
TKFIHQESDN LDVLTAGPRA PNPLLLLDSQ HMASLIDKFR TVYDYVLIDT PPIGVAVDAL
VVSKVADGIL VVVRPDVTDS NTANAAREAL VKSNQRVLGL AVNGVTRSDG SYHYYDGYYS
SDNDTTANGK TRSEKLGMER L
//
