ID B8K1C1_RABIT Unreviewed; 1216 AA.
AC B8K1C1;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Intersectin 1 isoform ITSN-l (Predicted), 5 prime {ECO:0000313|EMBL:ACK77502.1};
DE Flags: Fragment;
GN Name=ITSN1 {ECO:0000313|EMBL:ACK77502.1};
OS Oryctolagus cuniculus (Rabbit).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX NCBI_TaxID=9986 {ECO:0000313|EMBL:ACK77502.1};
RN [1] {ECO:0000313|EMBL:ACK77502.1}
RP NUCLEOTIDE SEQUENCE.
RA Antonellis A., Benjamin B., Blakesley R.W., Bouffard G.G., Brinkley C.,
RA Brooks S., Chu G., Chub I., Coleman H., Fuksenko T., Gestole M.,
RA Gregory M., Guan X., Gupta J., Gurson N., Han E., Han J., Hansen N.,
RA Hargrove A., Hines-Harris K., Ho S.-L., Hu P., Hunter G., Hurle B.,
RA Idol J.R., Johnson T., Knight E., Kwong P., Lee-Lin S.-Q., Legaspi R.,
RA Madden M., Maduro Q.L., Maduro V.B., Margulies E.H., Masiello C.,
RA Maskeri B., McDowell J., Merkulov G., Montemayor C., Mullikin J.C.,
RA Park M., Prasad A., Ramsahoye C., Reddix-Dugue N., Riebow N., Schandler K.,
RA Schueler M.G., Sison C., Smith L., Stantripop S., Thomas J.W., Thomas P.J.,
RA Tsipouri V., Young A., Green E.D.;
RT "NISC Comparative Sequencing Initiative.";
RL Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; DP001068; ACK77502.1; -; Genomic_DNA.
DR AlphaFoldDB; B8K1C1; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00052; EH; 2.
DR CDD; cd11987; SH3_Intersectin1_1; 1.
DR CDD; cd11991; SH3_Intersectin1_3; 1.
DR CDD; cd11995; SH3_Intersectin1_5; 1.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR Gene3D; 2.30.30.40; SH3 Domains; 5.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR000261; EH_dom.
DR InterPro; IPR032140; INTAP.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR11216; EH DOMAIN; 1.
DR PANTHER; PTHR11216:SF68; INTERSECTIN-1; 1.
DR Pfam; PF12763; EF-hand_4; 2.
DR Pfam; PF16617; INTAP; 1.
DR Pfam; PF00018; SH3_1; 3.
DR Pfam; PF07653; SH3_2; 1.
DR Pfam; PF14604; SH3_9; 1.
DR PRINTS; PR00499; P67PHOX.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00054; EFh; 2.
DR SMART; SM00027; EH; 2.
DR SMART; SM00326; SH3; 5.
DR SUPFAM; SSF47473; EF-hand; 2.
DR SUPFAM; SSF50044; SH3-domain; 5.
DR PROSITE; PS00018; EF_HAND_1; 2.
DR PROSITE; PS50222; EF_HAND_2; 2.
DR PROSITE; PS50031; EH; 2.
DR PROSITE; PS50002; SH3; 5.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 21..100
FT /note="EH"
FT /evidence="ECO:0000259|PROSITE:PS50031"
FT DOMAIN 53..88
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 221..310
FT /note="EH"
FT /evidence="ECO:0000259|PROSITE:PS50031"
FT DOMAIN 254..289
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 740..801
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 908..966
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 998..1056
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 1070..1134
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 1151..1210
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 328..348
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 653..702
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 801..863
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 969..994
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 355..509
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 330..348
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 829..863
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1216
FT /evidence="ECO:0000313|EMBL:ACK77502.1"
SQ SEQUENCE 1216 AA; 137159 MW; 2EB276EC80DDF2CB CRC64;
MAQFPTPFGG SLDVWAITVE ERAKHDQQFH SLKPRSGFIT GDQARNFFFQ SGLPQPVLAQ
IWALADMNND GRMDQVEFSI AMKLIKLKLQ GYQLPSALPP VMKQQPVAIS SAPAFGIGGI
ASMPPLTAVA PVPMGSIPVV GMSPPLVSSV PTAAVPPLAN GAPPVIQPLP AFTHPAATLP
KSSSFSRSGP GSQLNTKLQK AQSFDVASVP PAAEWAVPQS SRLKYRQLFN SHDKTMSGHL
TGPQARTILM QSSLPQAQLA SIWNLSDIDQ DGKLTAEEFI LAMHLIDVAM SGQPLPPVLP
PEYIPPSFRR VRSGSGISVI SSASVDQRLP EEPVLEDEQQ QLEKKLPVTF EDKKRENFER
GNLELEKRRQ ALLEQQRKEQ ERLAQLERAE QERKERERQE QERKRQLELE KQLEKQRELE
RQREEERRKE IERREAAKRE LERQRQLEWE RNRRQELLNQ RNKEQEDIVV LKAKKKTLEF
ELEALNDKKH QLEGKLQDIR CRLTTQRQEI ESTNKSRELR IAEITHLQQQ LQESQQMLGR
LIPEKQILND QLKQVQQNSL HRDSLLTLKR ALEAKELARQ QLRDQLDEVE KETRSKLQEI
DIFNNQLKEL REMHNKQQLQ KQKSIEAERL KQKEQERKII ELEKQKEEAQ RRAQERDKQW
LEHVQQEDEH QRPRKLQDED KLKREESVKK KEGEEKGKQE TQDKLSRFFH QHQEPAKPAV
QTPWPTAEKG PLTISAQENV KVVYYRALYP FESRSHDEIT IQPGDIVMVD ESQTGEPGWL
GGELKGKTGW FPANYAEKIP ENEVPTPAKP VTDATSAPAP KLALRETPAP SVVSSSEPST
TPNNWADFSS TWPSSTNEKP ETDNWDAWAA QPSLTVPSAG QLRQRSAFTP ATATGSSPSP
VLGQGEKVEG LQAQALYPWR AKKDNHLNFN KNDVITVLEQ QDMWWFGEVQ GQKGWFPKSY
VKLISGPIRK STSMESGPSE SPASRKRGAS PAAKATAASG EEFIAMYTYE SSEQGDLTFQ
QGDVILVTKK DGDWWTGTVG DKSGVFPSNY VRLKDSEGSG TAGKTGSLGK KPEIAQVIAS
YTATGPKQLT LAPGQLILIR KKNPGGWWEG ELQARGKKRQ IGWFPANYVK LLSPGTSKIT
PTEPPKSAAL PAVCQVIGMY DYTAQNDDEL AFNKGQIINV LNKEDPDWWK GEVNGQVGLF
PSNYVKLTTD MDPSQQ
//
