ID B8KPD4_9GAMM Unreviewed; 644 AA.
AC B8KPD4;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=Chaperone protein DnaK {ECO:0000256|ARBA:ARBA00014415, ECO:0000256|HAMAP-Rule:MF_00332};
DE AltName: Full=HSP70 {ECO:0000256|HAMAP-Rule:MF_00332};
DE AltName: Full=Heat shock 70 kDa protein {ECO:0000256|HAMAP-Rule:MF_00332};
DE AltName: Full=Heat shock protein 70 {ECO:0000256|HAMAP-Rule:MF_00332};
GN Name=dnaK {ECO:0000256|HAMAP-Rule:MF_00332,
GN ECO:0000313|EMBL:EED30968.1};
GN ORFNames=NOR53_411 {ECO:0000313|EMBL:EED30968.1};
OS gamma proteobacterium NOR5-3.
OC Bacteria; Pseudomonadota; Gammaproteobacteria.
OX NCBI_TaxID=566466 {ECO:0000313|EMBL:EED30968.1};
RN [1] {ECO:0000313|EMBL:EED30968.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NOR5-3 {ECO:0000313|EMBL:EED30968.1};
RA Amann R., Fuchs B., Ferriera S., Johnson J., Kravitz S., Beeson K.,
RA Sutton G., Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL Submitted (SEP-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Acts as a chaperone. {ECO:0000256|HAMAP-Rule:MF_00332}.
CC -!- INDUCTION: By stress conditions e.g. heat shock. {ECO:0000256|HAMAP-
CC Rule:MF_00332}.
CC -!- SIMILARITY: Belongs to the heat shock protein 70 family.
CC {ECO:0000256|ARBA:ARBA00007381, ECO:0000256|HAMAP-Rule:MF_00332,
CC ECO:0000256|RuleBase:RU003322}.
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DR EMBL; DS999408; EED30968.1; -; Genomic_DNA.
DR AlphaFoldDB; B8KPD4; -.
DR STRING; 566466.NOR53_411; -.
DR eggNOG; COG0443; Bacteria.
DR HOGENOM; CLU_005965_2_4_6; -.
DR OrthoDB; 9766019at2; -.
DR Proteomes; UP000003977; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR Gene3D; 1.20.1270.10; -; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR HAMAP; MF_00332; DnaK; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR012725; Chaperone_DnaK.
DR InterPro; IPR018181; Heat_shock_70_CS.
DR InterPro; IPR029048; HSP70_C_sf.
DR InterPro; IPR029047; HSP70_peptide-bd_sf.
DR InterPro; IPR013126; Hsp_70_fam.
DR NCBIfam; TIGR02350; prok_dnaK; 1.
DR PANTHER; PTHR19375:SF541; CHAPERONE PROTEIN DNAK; 1.
DR PANTHER; PTHR19375; HEAT SHOCK PROTEIN 70KDA; 1.
DR Pfam; PF00012; HSP70; 1.
DR PRINTS; PR00301; HEATSHOCK70.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR SUPFAM; SSF100934; Heat shock protein 70kD (HSP70), C-terminal subdomain; 1.
DR SUPFAM; SSF100920; Heat shock protein 70kD (HSP70), peptide-binding domain; 1.
DR PROSITE; PS00297; HSP70_1; 1.
DR PROSITE; PS00329; HSP70_2; 1.
DR PROSITE; PS01036; HSP70_3; 1.
PE 2: Evidence at transcript level;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW Rule:MF_00332};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|HAMAP-Rule:MF_00332};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW Rule:MF_00332};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|HAMAP-
KW Rule:MF_00332};
KW Stress response {ECO:0000256|ARBA:ARBA00023016, ECO:0000256|HAMAP-
KW Rule:MF_00332}.
FT REGION 602..644
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 199
FT /note="Phosphothreonine; by autocatalysis"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00332"
SQ SEQUENCE 644 AA; 68523 MW; C3625650563CE19B CRC64;
MGKIIGIDLG TTNSCVSVLE GGKPRVIENT EGDRTTPSIV GYTDDGEILV GQSAKRQAVT
NPHNTLYAVK RLIGRKFTDD VVQKDISMVP YKIVAADNGD AWVEVKGEKM APPQVSAEVL
RKMKKTAEEF LGEPVTEAVI TVPAYFNDSQ RQATKDAGKI AGLEVKRIIN EPTAAALAYG
MDKAKGDHTI AVYDLGGGTF DISIIEIAEV DGEHQFEVLS TNGDTFLGGE DFDMRLIEYL
AQQFKSESGI DLHNDPLALQ RLKEAAEKAK IELSHSQQTE VNLPYITADA TGPKHLVVKL
SRSKLESLVE ELVDRSIEPL KIALKDAGLS PSEIDDVILV GGQTRMPMVQ KKVADFFGKE
PRKDVNPDEA VAMGASIQGA VLAGDVKDVL LLDVTPLTLG IETMGGVATP LIDKNTTIPT
KKSQIFSTAD DNQTAVTIHV VQGERKQAAQ NKSLGRFDLA DIPPAQRGMP QIEVTFDLDA
NGILNVSAKD KATGKEQSIR ITASGGLSDD EIEAMVADAE VNAAADKQFE ELIASRNTCD
GLVHAAKKTL EEAGEHASDD EKAAIEAAVS EAEEALKGDD KDAIDAAATK LTEATGPVAQ
KMYAAQAEAA QGEAGPDASA DSGDSAGADD AVDAEFEEVS DDKK
//
