ID   B8KPS7_9GAMM            Unreviewed;       836 AA.
AC   B8KPS7;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   SubName: Full=Zn-dependent aminopeptidase {ECO:0000313|EMBL:EED30446.1};
GN   Name=pepN {ECO:0000313|EMBL:EED30446.1};
GN   ORFNames=NOR53_527 {ECO:0000313|EMBL:EED30446.1};
OS   gamma proteobacterium NOR5-3.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria.
OX   NCBI_TaxID=566466 {ECO:0000313|EMBL:EED30446.1};
RN   [1] {ECO:0000313|EMBL:EED30446.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NOR5-3 {ECO:0000313|EMBL:EED30446.1};
RA   Amann R., Fuchs B., Ferriera S., Johnson J., Kravitz S., Beeson K.,
RA   Sutton G., Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL   Submitted (SEP-2008) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; DS999409; EED30446.1; -; Genomic_DNA.
DR   AlphaFoldDB; B8KPS7; -.
DR   STRING; 566466.NOR53_527; -.
DR   eggNOG; COG0308; Bacteria.
DR   HOGENOM; CLU_015077_0_0_6; -.
DR   Proteomes; UP000003977; Unassembled WGS sequence.
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd09604; M1_APN_like; 1.
DR   Gene3D; 1.10.390.10; Neutral Protease Domain 2; 1.
DR   InterPro; IPR014782; Peptidase_M1_dom.
DR   InterPro; IPR027268; Peptidase_M4/M1_CTD_sf.
DR   PANTHER; PTHR11533:SF303; AMINOPEPTIDASE N; 1.
DR   PANTHER; PTHR11533; PROTEASE M1 ZINC METALLOPROTEASE; 1.
DR   Pfam; PF01433; Peptidase_M1; 1.
DR   SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE   4: Predicted;
KW   Aminopeptidase {ECO:0000313|EMBL:EED30446.1};
KW   Hydrolase {ECO:0000313|EMBL:EED30446.1};
KW   Protease {ECO:0000313|EMBL:EED30446.1}.
FT   DOMAIN          444..603
FT                   /note="Peptidase M1 membrane alanine aminopeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF01433"
FT   REGION          417..437
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          817..836
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        422..437
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   836 AA;  96055 MW;  6C5BAA0241446110 CRC64;
     MVGILIMRLR AVICVVGFFA AGFGSLSTST HAQEVIGSGA DAFAQLGQEL PTPNSYRTAS
     GAPGHEYWQQ QADYDIDARL NADARRIDAS ARIVYTNNSP DALRYLWLQL DQNRFKQDSL
     DRRSRTVSSD QVSYRNLREH QAVSIGDYGY RNLRFSGESG EELPFTVVDT MVRVDLPKPL
     ASGEYISFNL EWTFDIIERD TVRSRGGYEQ FYESDTQIFF LSQWFPRLAA YSDYDGWHNK
     AFLGSGEFTL EFGDYDVSLT VPDNHIISST GALANPDDVL TAQQKQRLAK AGSDKPTFIV
     TPEEALANEK SKATGTRTWR FEAENVRDFA WASSSKFIWD AMVHEQPGAK HERVYAMSFY
     PNEAEPVWSK YSTQAVVHTM DVYSRFSFDY PYPTAQSVNT WEGGGMEYPM ITFNGYRPDP
     PRANPEDPES AESRAEAERA YSRRIKYGLI GVVIHEVGHI YFPMVVNSDE RQWTWMDEGL
     NTFLEYVAEL EWEEDFPAFR RISDPLINEI NVLDMIPEYM MSPNQVPIMT QSDSVLRLGP
     NAYSKPAAAL TVLRETVMGR ELFDFAFREY ARRWQFKRPT PADFFRTMED ASGVDLDWFW
     RSWFYTTDYV DMAITDVRAY RLKHDDPDVD YPLDREEHAR DNPLPVNIER NQAEGIVPRE
     ERFEALKDLY SENDRYTVTN KDRNDAADKF DKLEPWEQRA FTQAIEDDNV FYFVDFENLG
     GVPSPLMLHI KYEDGSERDL EIPAEIWRKN AIKVTHRLIE DKPIAYIALD PRHQTADANY
     SNNRFPSAIH QSRLSAYKAD VVKRNLMADM LHELKDSAKM DSDDGKSAPL TPANGR
//