ID   B8KYQ4_9GAMM            Unreviewed;       298 AA.
AC   B8KYQ4;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   SubName: Full=Hydroxymethylglutaryl-CoA lyase {ECO:0000313|EMBL:EED41328.1};
DE            EC=4.1.3.4 {ECO:0000313|EMBL:EED41328.1};
GN   Name=mvaB {ECO:0000313|EMBL:EED41328.1};
GN   ORFNames=SSKA14_4353 {ECO:0000313|EMBL:EED41328.1};
OS   Stenotrophomonas sp. SKA14.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC   Xanthomonadaceae; Stenotrophomonas.
OX   NCBI_TaxID=391601 {ECO:0000313|EMBL:EED41328.1};
RN   [1] {ECO:0000313|EMBL:EED41328.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SKA14 {ECO:0000313|EMBL:EED41328.1};
RA   Hagstrom A., Ferriera S., Johnson J., Kravitz S., Beeson K., Sutton G.,
RA   Rogers Y.-H., Friedman R., Frazier M., Venter J.C.;
RL   Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the HMG-CoA lyase family.
CC       {ECO:0000256|ARBA:ARBA00009405}.
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DR   EMBL; DS999412; EED41328.1; -; Genomic_DNA.
DR   RefSeq; WP_008268685.1; NZ_DS999412.1.
DR   AlphaFoldDB; B8KYQ4; -.
DR   GeneID; 84606032; -.
DR   HOGENOM; CLU_022138_3_2_6; -.
DR   Proteomes; UP000003991; Unassembled WGS sequence.
DR   GO; GO:0004419; F:hydroxymethylglutaryl-CoA lyase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd07938; DRE_TIM_HMGL; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR043594; HMGL.
DR   InterPro; IPR000891; PYR_CT.
DR   PANTHER; PTHR42738; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR   PANTHER; PTHR42738:SF7; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR   Pfam; PF00682; HMGL-like; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
DR   PROSITE; PS50991; PYR_CT; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000313|EMBL:EED41328.1};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT   DOMAIN          5..272
FT                   /note="Pyruvate carboxyltransferase"
FT                   /evidence="ECO:0000259|PROSITE:PS50991"
SQ   SEQUENCE   298 AA;  31261 MW;  78EFE26DF418D7F1 CRC64;
     MSDYVRIVEV GPRDGLQNEK QSVSTADKIE LINRLSATGL RSIEATSFVS PKWIPQLADA
     AEVYAGIQRR PGIHYPVLVP NEQGYDRARA VGVEEVAVFT AASEAFNRTN TNAGIDESLA
     RFEPILRRAA ADGVRVRGYV STVLGCPYQG EVPLADVVRV ARALHQMGCY EISLGDTIGV
     GTPRKARAML QAVAAEIPMA ALAVHFHDTY GQAIANIATC LEEGVRVVDS AVSGAGGCPY
     AKGASGNVAS EDVVYLLQGL GLDSGVDLPA LAETGRWLAG LLGRATASRT GQALAAAG
//