ID   B8LMX8_PICSI            Unreviewed;       653 AA.
AC   B8LMX8;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 52.
DE   RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
OS   Picea sitchensis (Sitka spruce) (Pinus sitchensis).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Pinopsida; Pinidae; Conifers I; Pinales; Pinaceae; Picea.
OX   NCBI_TaxID=3332 {ECO:0000313|EMBL:ABR17008.1};
RN   [1] {ECO:0000313|EMBL:ABR17008.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Green portion of the leader tissue
RC   {ECO:0000313|EMBL:ABR17008.1};
RA   Ralph S.G., Chun H.E., Liao N., Ali J., Reid K., Kolosova N., Cooper N.,
RA   Cullis C., Jancsik S., Moore R., Mayo M., Wagner S., Holt R.A.,
RA   Jones S.J.M., Marra M.A., Ritland C.E., Ritland K., Bohlmann J.;
RT   "Full length cDNA sequences from Sitka Spruce (Picea sitchensis).";
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; EF677162; ABR17008.1; -; mRNA.
DR   AlphaFoldDB; B8LMX8; -.
DR   OMA; YENAFRR; -.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0006952; P:defense response; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR042197; Apaf_helical.
DR   InterPro; IPR044974; Disease_R_plants.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR11017:SF597; TIR DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   Pfam; PF01582; TIR; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SMART; SM00255; TIR; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50104; TIR; 1.
PE   2: Evidence at transcript level;
FT   DOMAIN          16..182
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|PROSITE:PS50104"
SQ   SEQUENCE   653 AA;  74339 MW;  3DD15EABD1549591 CRC64;
     MAASTSASAA ANPNKKSYQV FINHRGVDVK ETFARSLYLR LLEKGLMAFL DKEEMQQGYQ
     FFSQIERAIR TASVHLAIFS PRYAESDWCL NELLLMLESN APIIPVFYRV KPAEVRWMLG
     LYGEYLQSHE TKGRYDPNTI KKWRNALHQV ASSSGFELET CNGEELVLEL LDKVVKCLSE
     IMIKPDLYVA EYPTGLDCKL KDFEDTVLLQ QQQSGEPQLL GIVGLGGVGK TTMAKELFNR
     KKTDYNTSCF LSDVRDHAAT RSLNLLQSQL LKSLTGMDGN IVSVDQGKGM LMESLKSSKA
     LIVLDDVDHV DQVKALLPVQ THDLDSRSLI LITSRDMGVL RSSKIDKSSI YTLTWLNKQH
     SLELFCSHAF SQAYPLAGFE RLVDNFLHCC KGLPLSLKVF GALLYSKDIS QWEDELESLQ
     QILPSDIHET LIISYRSLNK EEKEIFLDIA CFFINQNRDA AISTWNGSGW RAKRGFLNLQ
     DKSLVEVDGE NCIHMHDHLR DLGRQVAASS SPLRLWRTEN VIEDLLHQSS DITVRGIRMV
     HDEYSGYDED DLFGVIDTEN AVLERILRRL QILHIEGSLL ERILMKVKLP NLLWFHWEKC
     PHSSLPAWVP IKNLRVLQVS HRRLNTMSFG EGEPQASLQL PESLEELRVY DCN
//