ID B8LU09_TALSN Unreviewed; 318 AA.
AC B8LU09;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Mitochondrial export translocase Oxa2, putative {ECO:0000313|EMBL:EED23839.1};
GN ORFNames=TSTA_072320 {ECO:0000313|EMBL:EED23839.1};
OS Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL
OS 1006) (Penicillium stipitatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC Talaromyces sect. Talaromyces.
OX NCBI_TaxID=441959 {ECO:0000313|EMBL:EED23839.1, ECO:0000313|Proteomes:UP000001745};
RN [1] {ECO:0000313|Proteomes:UP000001745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006
RC {ECO:0000313|Proteomes:UP000001745};
RX PubMed=25676766; DOI=10.1128/genomea.01559-14;
RA Nierman W.C., Fedorova-Abrams N.D., Andrianopoulos A.;
RT "Genome sequence of the AIDS-associated pathogen Penicillium marneffei
RT (ATCC18224) and its near taxonomic relative Talaromyces stipitatus
RT (ATCC10500).";
RL Genome Announc. 3:E0155914-E0155914(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU003945}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU003945}.
CC Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004448}.
CC -!- SIMILARITY: Belongs to the OXA1/ALB3/YidC family.
CC {ECO:0000256|ARBA:ARBA00009877, ECO:0000256|RuleBase:RU003945}.
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DR EMBL; EQ962652; EED23839.1; -; Genomic_DNA.
DR RefSeq; XP_002341226.1; XM_002341185.1.
DR AlphaFoldDB; B8LU09; -.
DR STRING; 441959.B8LU09; -.
DR GeneID; 8102331; -.
DR VEuPathDB; FungiDB:TSTA_072320; -.
DR eggNOG; KOG1239; Eukaryota.
DR HOGENOM; CLU_029282_1_2_1; -.
DR InParanoid; B8LU09; -.
DR OMA; IIVLWGQ; -.
DR OrthoDB; 1448664at2759; -.
DR PhylomeDB; B8LU09; -.
DR Proteomes; UP000001745; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0032977; F:membrane insertase activity; IEA:InterPro.
DR GO; GO:0051205; P:protein insertion into membrane; IEA:UniProt.
DR InterPro; IPR001708; YidC/ALB3/OXA1/COX18.
DR InterPro; IPR028055; YidC/Oxa/ALB_C.
DR PANTHER; PTHR12428:SF34; CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX18, MITOCHONDRIAL; 1.
DR PANTHER; PTHR12428; OXA1; 1.
DR Pfam; PF02096; 60KD_IMP; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792};
KW Reference proteome {ECO:0000313|Proteomes:UP000001745};
KW Transit peptide {ECO:0000256|ARBA:ARBA00022946};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003945};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 59..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 246..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 59..284
FT /note="Membrane insertase YidC/Oxa/ALB C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02096"
SQ SEQUENCE 318 AA; 35890 MW; 4023EC73D4898602 CRC64;
MRPPLTPRWF QLRRPVTSSI LFHRIRHFHA TRPAPLVAES VTLASDFLHG VHGVTGLPWA
ASIPLAAVCV RMVVAFPLLV WSRVTNRKMA DIAPLLLCLR NHYQQAVKAQ AMENKLYMRP
REAERQLRAH LKERTALLYK EWGISRTLGF LPLLQLPVWL ALMEGVRNIG QSMNLPGVEP
ALANGGAFWF PDLLAGDTTG ILPLALTLSI MANVRLGFTT KTFAELSDYK TPEMTRHLFL
KVVKEFLTFM SVYIGFTAYM TGMPAGMMLY WIASTNTATL QSKFLDFLFA SKRLQILPQM
HVRVLKPGEK PPPIKSLE
//
