ID   B8MJ76_TALSN            Unreviewed;       503 AA.
AC   B8MJ76;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   24-JAN-2024, entry version 43.
DE   RecName: Full=Integrase catalytic domain-containing protein {ECO:0000259|PROSITE:PS50994};
GN   ORFNames=TSTA_041430 {ECO:0000313|EMBL:EED14665.1};
OS   Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL
OS   1006) (Penicillium stipitatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC   Talaromyces sect. Talaromyces.
OX   NCBI_TaxID=441959 {ECO:0000313|EMBL:EED14665.1, ECO:0000313|Proteomes:UP000001745};
RN   [1] {ECO:0000313|Proteomes:UP000001745}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006
RC   {ECO:0000313|Proteomes:UP000001745};
RX   PubMed=25676766; DOI=10.1128/genomea.01559-14;
RA   Nierman W.C., Fedorova-Abrams N.D., Andrianopoulos A.;
RT   "Genome sequence of the AIDS-associated pathogen Penicillium marneffei
RT   (ATCC18224) and its near taxonomic relative Talaromyces stipitatus
RT   (ATCC10500).";
RL   Genome Announc. 3:E0155914-E0155914(2015).
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DR   EMBL; EQ962657; EED14665.1; -; Genomic_DNA.
DR   RefSeq; XP_002484618.1; XM_002484573.1.
DR   AlphaFoldDB; B8MJ76; -.
DR   STRING; 441959.B8MJ76; -.
DR   GeneID; 8109728; -.
DR   VEuPathDB; FungiDB:TSTA_041430; -.
DR   HOGENOM; CLU_542027_0_0_1; -.
DR   InParanoid; B8MJ76; -.
DR   OrthoDB; 2333235at2759; -.
DR   PhylomeDB; B8MJ76; -.
DR   Proteomes; UP000001745; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProt.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR025724; GAG-pre-integrase_dom.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   Pfam; PF13976; gag_pre-integrs; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50994; INTEGRASE; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001745};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW   Transposable element {ECO:0000256|ARBA:ARBA00022464}.
FT   DOMAIN          385..503
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50994"
FT   REGION          128..157
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          218..237
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   503 AA;  58213 MW;  09C694C2A95FA2B8 CRC64;
     MIKLLKEKLA PKENREKALL IKRERELTIP KRGTKPKELA KKWRELLMDM NLANFKALTS
     EQLARDFIDS TEGVLPKFHE LWSTTLLQYD LNSKMSTLSE PPTIEGILNE FDSWTDAYAK
     KELNPKPDIT MATFSNKSDQ PEKNNERSAT PKSNRKITCL DGEEHGFENC PYVNPEKRTS
     EWKPDPNIQK KFDVLEKDKT HPKAKKLRWV KKRIERKMKD DTSTDSNKNS DQQEQSNLVY
     DSDEFCGTVL DTVLSASGNK RDMKDEWILD SGSERKDEDL CNIKWHGRLI LLEWKNNKTP
     KSSLQYELAM SSFEKVTLKD PALAWHKRFG HISQKAVQKL EEATEGAVVT TSEILNRNPD
     GFQEKCEVCE MSKARRKISR VSMTKPTKPF QVLFVDIIVM NLAMNGHTYA LHAVDPYTKF
     HVITTTKTKS VNFTLETMIE EIEHTFKAHI DEVHLDGESS LNGISFTKYC RENKKRLLVT
     VPGTPERNNY RFKLIRFAAN YKL
//