ID B8MRQ2_TALSN Unreviewed; 843 AA.
AC B8MRQ2;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=Elongation factor 2 {ECO:0000256|ARBA:ARBA00017891};
GN ORFNames=TSTA_057050 {ECO:0000313|EMBL:EED13209.1};
OS Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL
OS 1006) (Penicillium stipitatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC Talaromyces sect. Talaromyces.
OX NCBI_TaxID=441959 {ECO:0000313|EMBL:EED13209.1, ECO:0000313|Proteomes:UP000001745};
RN [1] {ECO:0000313|Proteomes:UP000001745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006
RC {ECO:0000313|Proteomes:UP000001745};
RX PubMed=25676766; DOI=10.1128/genomea.01559-14;
RA Nierman W.C., Fedorova-Abrams N.D., Andrianopoulos A.;
RT "Genome sequence of the AIDS-associated pathogen Penicillium marneffei
RT (ATCC18224) and its near taxonomic relative Talaromyces stipitatus
RT (ATCC10500).";
RL Genome Announc. 3:E0155914-E0155914(2015).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; EQ962659; EED13209.1; -; Genomic_DNA.
DR RefSeq; XP_002487320.1; XM_002487275.1.
DR AlphaFoldDB; B8MRQ2; -.
DR STRING; 441959.B8MRQ2; -.
DR GeneID; 8109936; -.
DR VEuPathDB; FungiDB:TSTA_057050; -.
DR eggNOG; KOG0469; Eukaryota.
DR HOGENOM; CLU_002794_11_1_1; -.
DR InParanoid; B8MRQ2; -.
DR OMA; NRHNRFY; -.
DR OrthoDB; 166721at2759; -.
DR PhylomeDB; B8MRQ2; -.
DR Proteomes; UP000001745; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR CDD; cd01681; aeEF2_snRNP_like_IV; 1.
DR CDD; cd04096; eEF2_snRNP_like_C; 1.
DR CDD; cd01885; EF2; 1.
DR CDD; cd16261; EF2_snRNP_III; 1.
DR CDD; cd03700; EF2_snRNP_like_II; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR005517; Transl_elong_EFG/EF2_IV.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR42908:SF10; ELONGATION FACTOR 2; 1.
DR PANTHER; PTHR42908; TRANSLATION ELONGATION FACTOR-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF03764; EFG_IV; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SMART; SM00838; EFG_C; 1.
DR SMART; SM00889; EFG_IV; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Elongation factor {ECO:0000313|EMBL:EED13209.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000001745}.
FT DOMAIN 17..254
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
SQ SEQUENCE 843 AA; 93424 MW; 5222CEEBF3B43D61 CRC64;
MVHFTIEEIR ALMDRPANIR NMSVIAHVDH GKSTLTDSLV QRAGIISAAK AGEARFTDTR
ADEQERGITI KSTAISLYAH LPDEEDLKDI PQKVDGNEFL INLIDSPGHV DFSSEVTAAL
RVTDGALVVV DTVEGVCVQT ETVLRQALGE RIKPVVIINK VDRALLELQV SKEDLYQSFS
RTIESVNVII ATYFDKALGD VQVYPDRGTI AFGSGLHGWA FTVRQFAVKY AKKFGVDRKK
MMERLWGDNF FNPKTKKWTK SDTYEGKPLE RAFNQFILDP IFKIFAAITH NKKEEIATLV
EKLDIKLASE EKDLEGKALL KVVMRKFLPA ADALMEMMVL HLPSPVTAQK YRAETLYEGP
TDDEACISIR DCNAKGPLML YVSKMVPTSD KGRFFAFGRV FSGTVKSGLK VRIQGPNYTP
GKKEDLSIKA IQRTILMMGR FVEPIEDVPA GNIVGLVGVD QFLLKSGTLT TSETAHNLKV
MKFSVSPVVR RSVEVKNAND LPKLVEGLKR LSKSDPCVQV SINESGEHVV AGAGELHLEI
CLKDLEEDHA GVPLRISDPV TQYRETVGAK SSMTALSKSP NKHNRLYVDA EPLTEEVSQA
IESGKITPRD DFKARARVLA DDYGWDVTDA RKIWAFGPDT TGANLLVDQT KAVQYLNEIK
DSFVSGFQWA TREGPIAEEP MRSVRFNVMD VTLHADAIHR GGGQIIPTAR RVLYAATLLA
EPGLLEPIFN VEIQVPEQAM GGIYGVLTRR RGHVYTEEQR VGTPLFTVKA YMPVNESFGF
NGDLRAATGG QAFPQSVFDH WAILPGGSPL DPTTKPGQII AETRKRKGLK EQVPGYDNYY
DKL
//
