ID B8MRW8_TALSN Unreviewed; 1624 AA.
AC B8MRW8;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE SubName: Full=Kinesin family protein {ECO:0000313|EMBL:EED13302.1};
GN ORFNames=TSTA_057910 {ECO:0000313|EMBL:EED13302.1};
OS Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL
OS 1006) (Penicillium stipitatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces;
OC Talaromyces sect. Talaromyces.
OX NCBI_TaxID=441959 {ECO:0000313|EMBL:EED13302.1, ECO:0000313|Proteomes:UP000001745};
RN [1] {ECO:0000313|Proteomes:UP000001745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006
RC {ECO:0000313|Proteomes:UP000001745};
RX PubMed=25676766; DOI=10.1128/genomea.01559-14;
RA Nierman W.C., Fedorova-Abrams N.D., Andrianopoulos A.;
RT "Genome sequence of the AIDS-associated pathogen Penicillium marneffei
RT (ATCC18224) and its near taxonomic relative Talaromyces stipitatus
RT (ATCC10500).";
RL Genome Announc. 3:E0155914-E0155914(2015).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283}.
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DR EMBL; EQ962659; EED13302.1; -; Genomic_DNA.
DR RefSeq; XP_002487413.1; XM_002487368.1.
DR STRING; 441959.B8MRW8; -.
DR GeneID; 8108927; -.
DR VEuPathDB; FungiDB:TSTA_057910; -.
DR eggNOG; KOG0245; Eukaryota.
DR HOGENOM; CLU_001485_20_0_1; -.
DR InParanoid; B8MRW8; -.
DR OMA; RIDKPKR; -.
DR OrthoDB; 126886at2759; -.
DR PhylomeDB; B8MRW8; -.
DR Proteomes; UP000001745; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR CDD; cd22705; FHA_KIF1; 1.
DR CDD; cd01365; KISc_KIF1A_KIF1B; 1.
DR CDD; cd01233; PH_KIFIA_KIFIB; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 6.10.250.2520; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR022164; Kinesin-like.
DR InterPro; IPR022140; Kinesin-like_KIF1-typ.
DR InterPro; IPR032405; Kinesin_assoc.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR049780; PH_KIFIA_KIFIB.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR47117:SF3; KINESIN FAMILY MEMBER 14-LIKE; 1.
DR PANTHER; PTHR47117; STAR-RELATED LIPID TRANSFER PROTEIN 9; 1.
DR Pfam; PF12473; DUF3694; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF12423; KIF1B; 1.
DR Pfam; PF00225; Kinesin; 1.
DR Pfam; PF16183; Kinesin_assoc; 1.
DR Pfam; PF00169; PH; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00283};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00283}; Reference proteome {ECO:0000313|Proteomes:UP000001745};
KW Transferase {ECO:0000256|ARBA:ARBA00022676}.
FT DOMAIN 8..360
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT DOMAIN 1505..1615
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 609..645
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 754..819
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 609..625
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 109..116
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 1624 AA; 180979 MW; 47E8604D022723C1 CRC64;
MAPAGGGNIK VVVRVRPFNK IERNAKCIVQ MKGNQTVLIP PPGAAEKASK GGMKGTADGP
KTFAFDRSYW SFDKSSPNYA GQENLFGDLG VPLLDNAFQG YNNCIFAYGQ TGSGKSYSMM
GYGKEHGVIP KICQDMFKRI AVLQEDKNLT CTVEVSYLEI YNERVRDLLN PATKGNLKVR
EHPSTGPYVE DLAKLVVRSF QEIENLMDEG NKARTVAATN MNETSSRSHA VFTLTLTQKR
HDAETTMDTE KVAKISLVDL AGSERATSTG ATGARLKEGA EINRSLSTLG RVIAALADLS
SGKGKKGTLV PYRDSVLTWL LKDSLGGNSM TAMIAAISPA DINFEETLST LRYADSAKRI
KNHAVVNEDP NARMIRELKE ELAQLRSKLG GGAGGAIASG APMEESYPAD TPLDQQIVSI
AQPDGTVKKV SKAEIVEQLN QSEKLYKDLN QTWEEKLAKT EEIQKEREAA LEELGISIEK
GFVGLSTPKK MPHLVNLSDD PLLTECLVYN IKPGETRVGN IDQENGAEIR LNGSKIQQQH
CIFQNVDNVV TLVPSEGAAI MVNGLRIEKP TRLRSGCRII LGDFHIFRFN HPEEARAERV
EQSLLRHSVT TSQLGSPAPS RSHDRTVSKT GSDIDGEISR IDSPIPNRSG RDADWFYARR
EAASAILGPD QKISDLNDDE LDALFDDVQK ARAVRRGLLD NEEDTDSLSS FPVRDKYMSN
GTIDNFSLDT AITMPGTPRQ VDDEEGDSSL QAARDDMQRQ LDKQKGEFQE KLKADASHVD
VEELRQEKTR MEEALQSAKA EFEKQLKQQK EQYETHIKEM GHPVPKIYEN GFAKLDDKEI
EIAKFVVRLW SKRNYVRMAE SILQHASLLK EAQVMSQIMD KNVVFQFAII DEGHNMVSSY
DLVLNGISGE DDDALDTIKK PCVCARVIDF KHCVVHLWSI EKLQKRVQAM RQMHQYIDRP
DYIQHFKLEN PFSDTCPAQY SLVGDADIPL TAVFEMRVQD FSVEVVSPYT QSVIGIIRLS
LEPSSAQGPS STLKFNVVMR DMAGFAEREG TEVHAQLFVP GVSEEGGATT TQMISGFDEN
PVRFESVHSM SLPLSSPRTA SLKVCIYAKV TSMHLDKLLS WDDMRDSSET PAPSKRKTPR
IAETEFFTEE RHDVFSRIQI LELAESGEYL PVEVVQSNSM DAGTYQLHQG LQRRVAIHLT
HSSTENFPWE DVTNLRVGSV RLLDPWGKIP DQDFQTPDVP LRLVQEPMIK DNADGTSNLT
IIGQWDSSLH GSLLMDRTTA EKYRVQVTLR WDLVSSRVHE PIVFALDQTL VILGRNYVRP
QSILRQIWSS TRIVHSTVGM FSVVIRPVSA KRAADLWRMN TQNDYVKGEE LLTNWSPRKV
SLVRDFIASR KRRQRAAELE AARGALGTVS LVASPAKGSG RSTPLRNQEL SERQMNLMKR
YLNLWSTGKD PTEIILVNSN TEQPSNGNVS SNVPSIFSSD SASASEHGAT PRYVANVQTL
SKNATVAKAS YLMMPDDNST RWIRRFIELR GSYLHVYSVP DGDEINTINL RHARVDHDPD
FARLFEGPDG FSSRGSGVGR PNIFAVYGPQ NTFLFAARTE AQKVEWILKI DQSYFSNNAP
TNGR
//
