ID B8NG62_ASPFN Unreviewed; 340 AA.
AC B8NG62;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=Semialdehyde dehydrogenase NAD-binding domain-containing protein {ECO:0000259|Pfam:PF01118};
GN ORFNames=AFLA_132230 {ECO:0000313|EMBL:EED50461.1}, G4B84_005178
GN {ECO:0000313|EMBL:QMW29843.1};
OS Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357
OS / JCM 12722 / SRRC 167).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=332952 {ECO:0000313|EMBL:EED50461.1, ECO:0000313|Proteomes:UP000001875};
RN [1] {ECO:0000313|EMBL:EED50461.1, ECO:0000313|Proteomes:UP000001875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 /
RC SRRC 167 {ECO:0000313|Proteomes:UP000001875}, and NRRL3357
RC {ECO:0000313|EMBL:EED50461.1};
RX PubMed=25883274; DOI=10.1128/genomeA.00168-15;
RA Nierman W.C., Yu J., Fedorova-Abrams N.D., Losada L., Cleveland T.E.,
RA Bhatnagar D., Bennett J.W., Dean R., Payne G.A.;
RT "Genome sequence of Aspergillus flavus NRRL 3357, a strain that causes
RT aflatoxin contamination of food and feed.";
RL Genome Announc. 3:E0016815-E0016815(2015).
RN [2] {ECO:0000313|EMBL:QMW29843.1, ECO:0000313|Proteomes:UP000515286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL3357 {ECO:0000313|EMBL:QMW29843.1,
RC ECO:0000313|Proteomes:UP000515286};
RA Fountain J.C., Clevenger J.P., Nadon B., Youngblood R.C., Korani W.,
RA Chang P.-K., Starr D., Wang H., Isett B., Johnston H.R., Wiggins R.,
RA Chu Y., Agarwal G., Kemerait R.C., Pandey M.K., Bhatnagar D.,
RA Ozias-Akins P., Varshney R.K., Scheffler B.E., Vaughn J.N., Guo B.;
RT "Two New Chromosome-Level Aspergillus flavus Reference Genomes Reveal a
RT Large Insertion Potentially Contributing to Isolate Stress Tolerance and
RT Aflatoxin Production.";
RL Submitted (JUL-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; EQ963478; EED50461.1; -; Genomic_DNA.
DR EMBL; CP059868; QMW29843.1; -; Genomic_DNA.
DR RefSeq; XP_002379237.1; XM_002379196.1.
DR AlphaFoldDB; B8NG62; -.
DR STRING; 332952.B8NG62; -.
DR EnsemblFungi; EED50461; EED50461; AFLA_132230.
DR VEuPathDB; FungiDB:AFLA_005547; -.
DR eggNOG; KOG1502; Eukaryota.
DR HOGENOM; CLU_007383_12_2_1; -.
DR OMA; NKHIASV; -.
DR OrthoDB; 5143at2759; -.
DR Proteomes; UP000001875; Unassembled WGS sequence.
DR Proteomes; UP000515286; Chromosome 3.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR000534; Semialdehyde_DH_NAD-bd.
DR PANTHER; PTHR48079:SF8; NAD(P)-BD_DOM DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR48079; PROTEIN YEEZ; 1.
DR Pfam; PF01118; Semialdhyde_dh; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
FT DOMAIN 4..82
FT /note="Semialdehyde dehydrogenase NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF01118"
SQ SEQUENCE 340 AA; 36683 MW; 76F935733FC227EE CRC64;
MTRIFLTGVS GYIGGDVLYV LSEKHPEYDI TVLVRDADKG AKISQAYPKV RVVQGELDSA
VVEEEAQNAD VVVNAASAQN NKGAEAVFRG LTSSKRMKPG YWIQVSGATL LSAVDIEKGV
YGEPSDKIYS DIDGEEDIKA LIHKYAAKRL IDHFILNLPE TPLSPKTAVV YPPIIYGRGR
GPIKQRSVQI PELARITLQN KTGYQVGRGL STWSNVHITD ISQIFVTLVE KAVTGEQGPF
WNENGIYFAE NGAINFGEIG RLVAEEAAKL GLSSASVKEI SDSEANALSG HGSVLWGTNA
QEGAQRARKV LGWTPTGKSL QEEIADTVRV EAVSLGLLSA
//
