ID B8NS10_ASPFN Unreviewed; 325 AA.
AC B8NS10;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=OTU-like cysteine protease, putative {ECO:0000313|EMBL:EED47187.1};
GN ORFNames=AFLA_052410 {ECO:0000313|EMBL:EED47187.1}, G4B84_000191
GN {ECO:0000313|EMBL:QMW24946.1};
OS Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357
OS / JCM 12722 / SRRC 167).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=332952 {ECO:0000313|EMBL:EED47187.1, ECO:0000313|Proteomes:UP000001875};
RN [1] {ECO:0000313|EMBL:EED47187.1, ECO:0000313|Proteomes:UP000001875}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 200026 / FGSC A1120 / IAM 13836 / NRRL 3357 / JCM 12722 /
RC SRRC 167 {ECO:0000313|Proteomes:UP000001875}, and NRRL3357
RC {ECO:0000313|EMBL:EED47187.1};
RX PubMed=25883274; DOI=10.1128/genomeA.00168-15;
RA Nierman W.C., Yu J., Fedorova-Abrams N.D., Losada L., Cleveland T.E.,
RA Bhatnagar D., Bennett J.W., Dean R., Payne G.A.;
RT "Genome sequence of Aspergillus flavus NRRL 3357, a strain that causes
RT aflatoxin contamination of food and feed.";
RL Genome Announc. 3:E0016815-E0016815(2015).
RN [2] {ECO:0000313|EMBL:QMW24946.1, ECO:0000313|Proteomes:UP000515286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL3357 {ECO:0000313|EMBL:QMW24946.1,
RC ECO:0000313|Proteomes:UP000515286};
RA Fountain J.C., Clevenger J.P., Nadon B., Youngblood R.C., Korani W.,
RA Chang P.-K., Starr D., Wang H., Isett B., Johnston H.R., Wiggins R.,
RA Chu Y., Agarwal G., Kemerait R.C., Pandey M.K., Bhatnagar D.,
RA Ozias-Akins P., Varshney R.K., Scheffler B.E., Vaughn J.N., Guo B.;
RT "Two New Chromosome-Level Aspergillus flavus Reference Genomes Reveal a
RT Large Insertion Potentially Contributing to Isolate Stress Tolerance and
RT Aflatoxin Production.";
RL Submitted (JUL-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; EQ963483; EED47187.1; -; Genomic_DNA.
DR EMBL; CP059866; QMW24946.1; -; Genomic_DNA.
DR RefSeq; XP_002383367.1; XM_002383326.1.
DR AlphaFoldDB; B8NS10; -.
DR STRING; 332952.B8NS10; -.
DR EnsemblFungi; EED47187; EED47187; AFLA_052410.
DR VEuPathDB; FungiDB:AFLA_011137; -.
DR eggNOG; KOG2606; Eukaryota.
DR HOGENOM; CLU_034963_2_0_1; -.
DR OMA; PIILVYM; -.
DR OrthoDB; 242020at2759; -.
DR Proteomes; UP000001875; Unassembled WGS sequence.
DR Proteomes; UP000515286; Chromosome 1.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd22762; OTU_fungi_OTU2-like; 1.
DR Gene3D; 3.90.70.80; -; 1.
DR InterPro; IPR049771; OTU2-like_OTU.
DR InterPro; IPR003323; OTU_dom.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR PANTHER; PTHR12419:SF10; DEUBIQUITINASE OTUD6B; 1.
DR PANTHER; PTHR12419; OTU DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF02338; OTU; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS50802; OTU; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:EED47187.1};
KW Protease {ECO:0000313|EMBL:EED47187.1}.
FT DOMAIN 165..325
FT /note="OTU"
FT /evidence="ECO:0000259|PROSITE:PS50802"
FT REGION 1..152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..54
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..115
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 325 AA; 36692 MW; 571F528AD576AE83 CRC64;
MEELLAKHRK EQKDLQARIT QKKKSATKKT RRGINEECER LQRELSERHQ AEIAELNGEP
APPVDDLDDL SLNGTEEDKT QKDHADSSQN PPSIDNSPDT SSATSESSAS SPRPKKPNRQ
KARLARRAAE QAAQSAIAAE EAAKQTDHRG DEQEVMDGVF KRLGLKQVEI KPDGHCLYSA
IAYQLEMLGL GLKPDPKRII LENPTQSRID TVASPQHDGY RAVRAVTADF INEHHDDFVP
FMEEPVELYT RKIKLTAEWG GQLELLAIAR AYGVEINVIQ GDGRIEKIEG DTQEYDDEQK
SKRVIWLAYY RHTYGLGEHY NALMK
//
