ID B8YGA3_STRC0 Unreviewed; 314 AA.
AC B8YGA3;
DT 03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 03-MAR-2009, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE SubName: Full=Polyprenyl diphosphate synthase {ECO:0000313|EMBL:ACL68406.1};
GN Name=terp24 {ECO:0000313|EMBL:ACL68406.1};
OS Streptomyces peucetius subsp. caesius ATCC 27952.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=316280 {ECO:0000313|EMBL:ACL68406.1};
RN [1] {ECO:0000313|EMBL:ACL68406.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 27952 {ECO:0000313|EMBL:ACL68406.1};
RX PubMed=19767465; DOI=10.1128/AEM.01402-09;
RA Ghimire G.P., Lee H.C., Sohng J.K.;
RT "Improved squalene production via modulation of the methylerythritol 4-
RT phosphate pathway and heterologous expression of genes from Streptomyces
RT peucetius ATCC 27952 in Escherichia coli.";
RL Appl. Environ. Microbiol. 75:7291-7293(2009).
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|ARBA:ARBA00006706, ECO:0000256|RuleBase:RU004466}.
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DR EMBL; FJ529814; ACL68406.1; -; Genomic_DNA.
DR AlphaFoldDB; B8YGA3; -.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR12001:SF71; (2E,6E)-FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SFLD; SFLDG01017; Polyprenyl_Transferase_Like; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Transferase {ECO:0000256|RuleBase:RU004466}.
SQ SEQUENCE 314 AA; 33496 MW; D6BD09459FB4DC30 CRC64;
MDTVAAYHFG WIDAQGRPSD GDGGKAVRPA LALLSAEAAG AAPEVGVPGA VAVELVHNFS
LLHDDLMDGD EQRRHRDTVW KVHGPAQAIL VGDALFALAN EVLLEIGTVE AGRATRRLTT
ATRKLIDGQA QDISYEHRER VTVEECLEME GNKTGALLAC AVSIGAVLGG ADDRTADTLE
SYGYHLGLAF QAVDDLLGIW GDPVATGKQT WSDLRQRKKS LPVVAALAAG GPASERLGEL
LAADAKSNDV DSFSEEEFAT RAALIEEAGG REWTSQEARR QHTVAIEALS GVDMPERVRA
QLVALADFVV VRKR
//
