ID B9BC17_9BURK Unreviewed; 400 AA.
AC B9BC17;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Secretion protein HlyD family {ECO:0000313|EMBL:EED98289.1};
GN ORFNames=BURMUCGD1_0188 {ECO:0000313|EMBL:EED98289.1};
OS Burkholderia multivorans CGD1.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX NCBI_TaxID=513051 {ECO:0000313|EMBL:EED98289.1, ECO:0000313|Proteomes:UP000005493};
RN [1] {ECO:0000313|EMBL:EED98289.1, ECO:0000313|Proteomes:UP000005493}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGD1 {ECO:0000313|EMBL:EED98289.1,
RC ECO:0000313|Proteomes:UP000005493};
RX PubMed=23105085; DOI=10.1128/JB.01306-12;
RA Varga J.J., Losada L., Zelazny A.M., Brinkac L., Harkins D., Radune D.,
RA Hostetler J., Sampaio E.P., Ronning C.M., Nierman W.C., Greenberg D.E.,
RA Holland S.M., Goldberg J.B.;
RT "Draft Genome Sequence Determination for Cystic Fibrosis and Chronic
RT Granulomatous Disease Burkholderia multivorans Isolates.";
RL J. Bacteriol. 194:6356-6357(2012).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EED98289.1}.
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DR EMBL; ACFB01000010; EED98289.1; -; Genomic_DNA.
DR RefSeq; WP_006401336.1; NZ_ACFB01000010.1.
DR AlphaFoldDB; B9BC17; -.
DR Proteomes; UP000005493; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469:SF15; HLYD FAMILY OF SECRETION PROTEINS; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 24..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 66..313
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
SQ SEQUENCE 400 AA; 42243 MW; 318181701C68D5EF CRC64;
MPDHNLDKLK IDRGPIAAPR RRRWVRYAAA TALALVALAI GLAVTRRPTV DTTAVTSAYP
YQNDTQLNAT GYVVPQRKAA VASKGQGRVE WLGVLEGTRV KKDEIIARLE SRDVEASLAQ
ALAQVKVARA NLGVQQAELK DAEIALRRTA ALAPRGAVPA AQLDTDTARV NKARASVNSG
EAAVASAEAN ARAAQVAVDQ TVIRAPFDGI VLAKHANVGD NITPFSSASD SKGAVVTIAD
MDTLEVEADV AESNIAKIRA GQPCEIQLDA LPDMRFAGRV SRIVPTVDRS KATVLVKVRF
VDRDDRVLPD MSAKIAFLSK PVSAQDRQPV TAVQASAVVE RDGRPVVFAL QDDTVHAVPV
ARGARIGELV AVRGVKPGDT VVLAPGAALK DGAKVTVAKK
//
