ID B9BF55_9BURK Unreviewed; 395 AA.
AC B9BF55;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE SubName: Full=Beta-ketoacyl synthase {ECO:0000313|EMBL:EED97418.1};
GN ORFNames=BURMUCGD1_4600 {ECO:0000313|EMBL:EED97418.1};
OS Burkholderia multivorans CGD1.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX NCBI_TaxID=513051 {ECO:0000313|EMBL:EED97418.1, ECO:0000313|Proteomes:UP000005493};
RN [1] {ECO:0000313|EMBL:EED97418.1, ECO:0000313|Proteomes:UP000005493}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGD1 {ECO:0000313|EMBL:EED97418.1,
RC ECO:0000313|Proteomes:UP000005493};
RX PubMed=23105085; DOI=10.1128/JB.01306-12;
RA Varga J.J., Losada L., Zelazny A.M., Brinkac L., Harkins D., Radune D.,
RA Hostetler J., Sampaio E.P., Ronning C.M., Nierman W.C., Greenberg D.E.,
RA Holland S.M., Goldberg J.B.;
RT "Draft Genome Sequence Determination for Cystic Fibrosis and Chronic
RT Granulomatous Disease Burkholderia multivorans Isolates.";
RL J. Bacteriol. 194:6356-6357(2012).
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EED97418.1}.
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DR EMBL; ACFB01000016; EED97418.1; -; Genomic_DNA.
DR RefSeq; WP_006402441.1; NZ_ACFB01000016.1.
DR AlphaFoldDB; B9BF55; -.
DR Proteomes; UP000005493; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd00834; KAS_I_II; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF320; BETA-KETOACYL SYNTHASE; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Transferase {ECO:0000256|RuleBase:RU003694}.
FT DOMAIN 1..395
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 395 AA; 40421 MW; 98054FDC2A14D610 CRC64;
MNSTRTPVYL SAPGMINALG ATTEDIVAAL RAGTAPGMGP RSDVAGGGWV GRAVSTLDVA
PPATLAHFDC RNNRLLLAAL AQIRPGIDAA IERYGPRRIG VVIGTSTSGI QAAEHALAQR
AATGAMPPGF DYRQMEIGTA APFVRAVLGV TGPAYTLSTA CTSSAKAFAA ARRLLRLKLC
DAVVVGGADS LCELTLQGFA SLESVSPTRT NPMSRNRNGI NIGEGAALFL MGRDETAVRL
AGVGESSDAH HISAPDPAGH GAEDALRAAL ADAGVASSAI GYVNLHATAT RLNDEMEANV
TARVFPHGVP ASGTKPLTGH MLGAAGATEL GFAWLVLARG IPLPRHHWDG EHDAALPALD
LVDGDRHLGS DATGRYAMSN SFAFGGSNAS LILGA
//
