ID   B9BS24_9BURK            Unreviewed;       785 AA.
AC   B9BS24;
DT   24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   24-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   SubName: Full=Phospholipase, patatin family {ECO:0000313|EMBL:EEE06595.1};
GN   ORFNames=BURMUCGD2_4192 {ECO:0000313|EMBL:EEE06595.1};
OS   Burkholderia multivorans CGD2.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=513052 {ECO:0000313|EMBL:EEE06595.1, ECO:0000313|Proteomes:UP000004535};
RN   [1] {ECO:0000313|EMBL:EEE06595.1, ECO:0000313|Proteomes:UP000004535}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGD2 {ECO:0000313|EMBL:EEE06595.1,
RC   ECO:0000313|Proteomes:UP000004535};
RX   PubMed=23105085; DOI=10.1128/JB.01306-12;
RA   Varga J.J., Losada L., Zelazny A.M., Brinkac L., Harkins D., Radune D.,
RA   Hostetler J., Sampaio E.P., Ronning C.M., Nierman W.C., Greenberg D.E.,
RA   Holland S.M., Goldberg J.B.;
RT   "Draft Genome Sequence Determination for Cystic Fibrosis and Chronic
RT   Granulomatous Disease Burkholderia multivorans Isolates.";
RL   J. Bacteriol. 194:6356-6357(2012).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EEE06595.1}.
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DR   EMBL; ACFC01000006; EEE06595.1; -; Genomic_DNA.
DR   AlphaFoldDB; B9BS24; -.
DR   Proteomes; UP000004535; Unassembled WGS sequence.
DR   GO; GO:0019867; C:outer membrane; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-UniRule.
DR   CDD; cd07205; Pat_PNPLA6_PNPLA7_NTE1_like; 1.
DR   Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 2.
DR   Gene3D; 3.10.20.310; membrane protein fhac; 1.
DR   Gene3D; 2.40.160.50; membrane protein fhac: a member of the omp85/tpsb transporter family; 1.
DR   InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR   InterPro; IPR010827; BamA/TamA_POTRA.
DR   InterPro; IPR043864; Omp85-like_dom.
DR   InterPro; IPR002641; PNPLA_dom.
DR   PANTHER; PTHR14226; NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER; 1.
DR   PANTHER; PTHR14226:SF82; PATATIN-LIKE PROTEIN, PLPD; 1.
DR   Pfam; PF19143; Omp85_2; 1.
DR   Pfam; PF01734; Patatin; 1.
DR   Pfam; PF07244; POTRA; 1.
DR   SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR   PROSITE; PS51635; PNPLA; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..785
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5002880159"
FT   DOMAIN          72..264
FT                   /note="PNPLA"
FT                   /evidence="ECO:0000259|PROSITE:PS51635"
FT   REGION          29..53
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        29..51
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   785 AA;  83473 MW;  4ECCBD6B415FAE2A CRC64;
     MLVALWCATA AAQPLPAAGT AATVSVSGSA PASTSATSAT STASTASGPT DGAASHVCVA
     DGGPSGRPSI GLALSGGGAR GYAHLGVLKV LEDNRIPIDC IAGTSMGAVV GGLYASGMPA
     EDMQKRLSQI DLADIAFDVT ERADLPQSRR EDERYYINGL TLGFGAKGVK APAGLVQGNR
     LQALLADWTA SVPTNQPFDR LPIPYRAVAT DLQTGQMVVL DHGSLPLAIR ASMAMPGLFA
     PAEINGRALV DGGLVSNLPV DTARRMGADV VIAVDIGSPL RPLDALASPA DVMQQMVGIL
     IRQNVTSQRK QLHAEDVLLT PDLGTIAFTD FQSANQAIAA GAAAATAALP RLKRFALTPE
     QYAAYKTAHA QPLPPPIRIT SIDIRTNGGV PKRVVNDALH VRPGDLYDPQ AVSKDLLALT
     TSGNFESVTQ QVISEGDENR LVIDAREKYW GPNFLLFGLG MSSSSTDEGG FRLHLGYRRP
     WLTESGLEFR ADTTLGSDRQ SARVELRQPL SASTGLYVAP YAEYQRRFAN VYLDDIKLTQ
     YRLQTERAGI DFGIPIRRLG DFRIGLAYAH GHASPDYNVP ADFGPNGEPT AFLFDGTNGR
     QLSARARLLI DQLDDPQFPR KGYFGELRVE RSFVSSEAQQ YTEVFGKAMV AQQFGRHSVN
     ASIEAGKSFG GVSPVNLLDF TLGGFQHLAA YAADQLNGNA LVYGQVTYMN QLMTFNASPV
     KALFVGASAE LGNVWSLDSP VSAGPLKQSY SFFTSLTTSF GPLYVGVALA PGGRHNLYFQ
     LGRTY
//