ID B9E2H7_CLOK1 Unreviewed; 817 AA.
AC B9E2H7;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE RecName: Full=Nucleotidyltransferase {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=CKR_1651 {ECO:0000313|EMBL:BAH06702.1};
OS Clostridium kluyveri (strain NBRC 12016).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=583346 {ECO:0000313|EMBL:BAH06702.1, ECO:0000313|Proteomes:UP000007969};
RN [1] {ECO:0000313|Proteomes:UP000007969}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 12016 {ECO:0000313|Proteomes:UP000007969};
RA Inui M., Nonaka H., Shinoda Y., Ikenaga Y., Abe M., Naito K., Vertes A.A.,
RA Yukawa H.;
RT "Complete genome sequence of Clostridium kluyveri and comparative genomics
RT of Clostridia species.";
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the phosphohexose mutase family.
CC {ECO:0000256|ARBA:ARBA00010231}.
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DR EMBL; AP009049; BAH06702.1; -; Genomic_DNA.
DR AlphaFoldDB; B9E2H7; -.
DR KEGG; ckr:CKR_1651; -.
DR HOGENOM; CLU_017652_1_0_9; -.
DR Proteomes; UP000007969; Chromosome.
DR GO; GO:0016868; F:intramolecular phosphotransferase activity; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd05805; MPG1_transferase; 1.
DR CDD; cd04181; NTP_transferase; 1.
DR Gene3D; 3.40.120.10; Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3; 3.
DR Gene3D; 3.30.310.50; Alpha-D-phosphohexomutase, C-terminal domain; 1.
DR Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR InterPro; IPR005844; A-D-PHexomutase_a/b/a-I.
DR InterPro; IPR016055; A-D-PHexomutase_a/b/a-I/II/III.
DR InterPro; IPR036900; A-D-PHexomutase_C_sf.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR InterPro; IPR011004; Trimer_LpxA-like_sf.
DR PANTHER; PTHR22572:SF15; MANNOSE-1-PHOSPHATE GUANYLTRANSFERASE BETA; 1.
DR PANTHER; PTHR22572; SUGAR-1-PHOSPHATE GUANYL TRANSFERASE; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR Pfam; PF02878; PGM_PMM_I; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR SUPFAM; SSF55957; Phosphoglucomutase, C-terminal domain; 1.
DR SUPFAM; SSF53738; Phosphoglucomutase, first 3 domains; 2.
DR SUPFAM; SSF51161; Trimeric LpxA-like enzymes; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 5..235
FT /note="Nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF00483"
FT DOMAIN 385..516
FT /note="Alpha-D-phosphohexomutase alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF02878"
SQ SEQUENCE 817 AA; 91253 MW; 81AC190E5C06B88B CRC64;
MMVVKAVIMA GGEGTRLRPL TCNIPKPMMP VMGKPIMEYA LELLKNTGIE DIGATLQYLP
DEIINYFGDG RDFGVNISYF VEETPLGTAG SVKNAEAFLN DTFIVISGDA LTDIDLSRAI
SYHKSKGAVA TLVLKEEPVP LEFGVVVTDD KGKVTGFLEK PGWGEVFSDK VNTGIYILEP
EIFKYYGKNK KCDFSSELFP LLLKEKAAVF GYVAEGYWCD IGNIDQYMKC HFDILKGFAN
VNIKAQKYSE DIWIGEDCEI SPQAKISTPV YIGKGSKIYK NAQIGPYTVL GENNIICSDA
TIKRSVLFNN CYIGDKAQIR GAVLCKKVQV KSKCSVFEEA ALGNDTIIKD KAIIKPGVKI
WPNKIIESGT LVNSNIIWKE KASKSIFGRN GISGEINVDI TPECVSKLGS AYGSVLKADS
RVAIACSDNG AAQMFKYSLA TGLLSMGLEV MDLKKMPMAF IRQSILFFGA QAGIYVCVNR
NAPEKVTIIF MDKNGLNIDR GMERKIESSF TREDFRRVKP DKFKHMEHIY NCLEYYKRQL
VNGFSLENIK NQKYRAVLSI EDPMVLEVIT GVLKELKVEV KLYDKFGDTE GLAQKVIEDS
ANLGIEIDEE CERPVIIDEK GSIIKDNLYD ALNALVMLKT HDIRTLVVPV TASSTMEKLA
KICGCKFIRT KTAHKVILET YLKNTTGINK RDMVSAYLMT LDAVSVCSMI INFMANCNRT
LSQITSIIPK YYTMKKEIKC PWNMKGRLMR NLIEENTSKS VDLIEGVKLN FEDGWTLVMP
DAEEPLCKIY TECSDYKKLN KLTEDILTQI TTITSEC
//
