ID B9K8J5_THENN Unreviewed; 594 AA.
AC B9K8J5;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Radical SAM domain protein {ECO:0000313|EMBL:ACM23278.1};
GN OrderedLocusNames=CTN_1102 {ECO:0000313|EMBL:ACM23278.1};
OS Thermotoga neapolitana (strain ATCC 49049 / DSM 4359 / NBRC 107923 / NS-E).
OC Bacteria; Thermotogota; Thermotogae; Thermotogales; Thermotogaceae;
OC Thermotoga.
OX NCBI_TaxID=309803 {ECO:0000313|EMBL:ACM23278.1, ECO:0000313|Proteomes:UP000000445};
RN [1] {ECO:0000313|Proteomes:UP000000445}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49049 / DSM 4359 / NBRC 107923 / NS-E
RC {ECO:0000313|Proteomes:UP000000445};
RA Lim S.K., Kim J.S., Cha S.H., Park B.C., Lee D.S., Tae H.S., Kim S.-J.,
RA Kim J.J., Park K.J., Lee S.Y.;
RT "The genome sequence of the hyperthermophilic bacterium Thermotoga
RT neapolitana.";
RL Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACM23278.1, ECO:0000313|Proteomes:UP000000445}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49049 / DSM 4359 / NBRC 107923 / NS-E
RC {ECO:0000313|Proteomes:UP000000445};
RX PubMed=19129632; DOI=10.1271/bbb.80567;
RA Lee D., Seo H., Park C., Park K.;
RT "WeGAS: a web-based microbial genome annotation system.";
RL Biosci. Biotechnol. Biochem. 73:213-216(2009).
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DR EMBL; CP000916; ACM23278.1; -; Genomic_DNA.
DR RefSeq; WP_015919593.1; NC_011978.1.
DR AlphaFoldDB; B9K8J5; -.
DR STRING; 309803.CTN_1102; -.
DR KEGG; tna:CTN_1102; -.
DR eggNOG; COG1032; Bacteria.
DR HOGENOM; CLU_011543_3_3_0; -.
DR Proteomes; UP000000445; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR045784; Radical_SAM_N2.
DR InterPro; IPR007197; rSAM.
DR PANTHER; PTHR42731:SF1; RADICAL SAM DOMAIN PROTEIN; 1.
DR PANTHER; PTHR42731; SLL1084 PROTEIN; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR Pfam; PF19864; Radical_SAM_N2; 1.
DR SFLD; SFLDG01082; B12-binding_domain_containing; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 218..446
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 594 AA; 68933 MW; 8D3BA4AC1B2BB07A CRC64;
MRTSLLYKIK EEERILPSKN LKGNEIIFIL AFPDIYKYGL PNLGIQTLYK ELYLRDDVAV
DRYYTDEDQP FSFEYGFKLK DSDFIGISFQ YEGIVLNAFK ILKAGSIPLI NLLREENDPI
IIGGGPVANY NPLPLSLVCD VIVLGEAEEA IHKIIDSYKV YRNVKRKRMK FLQAVSQIEG
IYVPCIHGFF QTGMVKQTSP VDINEHPAHS IFVTKNTVYE ERVFSIEVRR GCTQRCRFCY
MGHRLKPPRT LRWETFKKIV DLAIDQCNVE IIKLFYEGLE TRIVEHYLEY IIKKGGRVRI
GSQRLEKLSK RIIEIAAISG QRKITVAPET SGRLRKVIGK HEIKDEEILE VVRISSLYGI
PDFGLYFILA IPGETFEDLD KIADLIMKVR HQMNKLKNTD GRLEIGINPL YPKPFTPFQY
VKLPSLKNIE DRFLYIVEKV KKEGFPVVIS NDVVDEKVEK RQKDENENES LVKFETTVFH
PISLLQPMIS RGGLEIAFLL HYLHSKRFNT VSDLENLLNE FGINAAWYFE EYIDKYCPWK
IQKTLISEDY LLREYFKALN FISTDEECKL NCSQCFNRCI DISTTNYQGG MSNA
//
