ID   B9L350_THERP            Unreviewed;       696 AA.
AC   B9L350;
DT   24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   24-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 76.
DE   SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:ACM06460.1};
GN   OrderedLocusNames=trd_A0214 {ECO:0000313|EMBL:ACM06460.1};
OS   Thermomicrobium roseum (strain ATCC 27502 / DSM 5159 / P-2).
OG   Plasmid Tros {ECO:0000313|Proteomes:UP000000447}.
OC   Bacteria; Thermomicrobiota; Thermomicrobia; Thermomicrobiales;
OC   Thermomicrobiaceae; Thermomicrobium.
OX   NCBI_TaxID=309801 {ECO:0000313|EMBL:ACM06460.1, ECO:0000313|Proteomes:UP000000447};
RN   [1] {ECO:0000313|EMBL:ACM06460.1, ECO:0000313|Proteomes:UP000000447}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27502 / DSM 5159 / P-2
RC   {ECO:0000313|Proteomes:UP000000447};
RC   PLASMID=Tros {ECO:0000313|Proteomes:UP000000447};
RX   PubMed=19148287; DOI=10.1371/journal.pone.0004207;
RA   Wu D., Raymond J., Wu M., Chatterji S., Ren Q., Graham J.E., Bryant D.A.,
RA   Robb F., Colman A., Tallon L.J., Badger J.H., Madupu R., Ward N.L.,
RA   Eisen J.A.;
RT   "Complete genome sequence of the aerobic CO-oxidizing thermophile
RT   Thermomicrobium roseum.";
RL   PLoS ONE 4:E4207-E4207(2009).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; CP001276; ACM06460.1; -; Genomic_DNA.
DR   RefSeq; WP_012642447.1; NC_011961.1.
DR   AlphaFoldDB; B9L350; -.
DR   KEGG; tro:trd_A0214; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_27_0; -.
DR   OrthoDB; 138587at2; -.
DR   Proteomes; UP000000447; Plasmid Tros.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd11386; MCP_signal; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 2.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR024478; HlyB_4HB_MCP.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   PANTHER; PTHR32089:SF119; METHYL-ACCEPTING CHEMOTAXIS PROTEIN TLPQ; 1.
DR   Pfam; PF12729; 4HB_MCP_1; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 3.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius}; Plasmid {ECO:0000313|EMBL:ACM06460.1};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        187..207
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          229..282
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          343..593
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   REGION          390..413
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          662..696
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        391..405
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   696 AA;  73681 MW;  873F98D2B866CB15 CRC64;
     MTIGFREKVL GILAAMAAIF VLLGAIGWFW LGQTRSAVQQ VNGMNEALTV LGQTARRMAE
     VRANVVAHVG ATTNADYRRQ LDERIAELDN QIAQGLDQLQ ALAHTPEELE RMAAVREAWT
     TYRASAERTL QLSRKYDLVA AQQNMTGDAA QKFAALQDAI RNLEQASSQD AQAIAQRAES
     QLTMLRFAML GAAGLAVVAF LGGLLVLRPA LRTVAEIAGA SQQLAEQELA ALEAALGKLA
     AGDLTARFAV TMEPLPVRGR DELARMAQSF NRMLERLRAV GSAFGNALEN LTQLVGQVRL
     AVRQVGEAGA QAQALSAQIA EASNAVARTI QDVAQGSATQ AEQVSSASSA VEEMSQTIQA
     VAKAAQEQGR ALQRATELVQ QMADRNQRAG ELARGVTERA GRNREQAESG SAVVQRTLST
     MDRVRAQVEE TARAIQELGE RSKQIGQIVQ VITDLTEQTN LLALNAAIEA ARAGEAGKGF
     AVVAEEVRKL AERSAASTQE IAQMVQGIQR TVEQAVAAMA ESAGSVTQVS SEAREVAEVF
     AAIRQAAEEV AERNRELLAS LEEIAKRSSE LRATMEDTAA IAEENAASAS ELSSTAEQVR
     GSIRRVTGVA EQNAAAAEEV SAATEQMATQ VGEIAAAAGQ LVGLADQLAR LVERFRVAAG
     EPARAPVEAN GRGWSEPAAS RVPVSAGANG NGRGAW
//