ID B9L7P4_NAUPA Unreviewed; 614 AA.
AC B9L7P4;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=Diguanylate cyclase/phosphodiesterase domain 1 {ECO:0000313|EMBL:ACM92128.1};
GN OrderedLocusNames=NAMH_0228 {ECO:0000313|EMBL:ACM92128.1};
OS Nautilia profundicola (strain ATCC BAA-1463 / DSM 18972 / AmH).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Nautiliales;
OC Nautiliaceae; Nautilia.
OX NCBI_TaxID=598659 {ECO:0000313|EMBL:ACM92128.1, ECO:0000313|Proteomes:UP000000448};
RN [1] {ECO:0000313|EMBL:ACM92128.1, ECO:0000313|Proteomes:UP000000448}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1463 / DSM 18972 / AmH
RC {ECO:0000313|Proteomes:UP000000448};
RX PubMed=19197347; DOI=10.1371/journal.pgen.1000362;
RA Campbell B.J., Smith J.L., Hanson T.E., Klotz M.G., Stein L.Y., Lee C.K.,
RA Wu D., Robinson J.M., Khouri H.M., Eisen J.A., Cary S.C.;
RT "Adaptations to submarine hydrothermal environments exemplified by the
RT genome of Nautilia profundicola.";
RL PLoS Genet. 5:E1000362-E1000362(2009).
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DR EMBL; CP001279; ACM92128.1; -; Genomic_DNA.
DR RefSeq; WP_012663500.1; NC_012115.1.
DR AlphaFoldDB; B9L7P4; -.
DR STRING; 598659.NAMH_0228; -.
DR KEGG; nam:NAMH_0228; -.
DR eggNOG; COG0834; Bacteria.
DR eggNOG; COG3706; Bacteria.
DR HOGENOM; CLU_026636_0_0_7; -.
DR OrthoDB; 5372104at2; -.
DR Proteomes; UP000000448; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd01007; PBP2_BvgS_HisK_like; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00497; SBP_bac_3; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00062; PBPb; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 435..453
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 487..614
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 614 AA; 71346 MW; DD0ED014F2602C1F CRC64;
MRFIFLFLSV FLFADMNVNV YVDKNFKIEL PKPFIKKEFK YLNKEGFFIL SYDKLPLIVE
NNLSVIAGIG HLKTYIYTHK NLKDIKVIGN ANLPVKIMFN VIGDVKYIDS SIEDFKQNKI
DAIVLNKKVY IKDAFLYDLD NFGIEFNKFY LVAYKDFLNK YKDAASFLSA YFPKAKTNSS
LILTGYYLKR KVNISSIYDD MFKEVVAKKL KVAVTPYWPP FDLEVHGELK GIGIDFWKLI
AKKAELDYEI VSEPIWIKIL NGIKEKKYDI TPNTSSTPDR KKYAIFSKPY VEFPLAIACR
NDLDIKSIDD IQSLAVGYHY TAHKMMKQHY PYLNYVPAKS VIDAFELVKN KKAQCVVDVL
PTIVWLMNQN NIGSMRIFFK TPFTFKLQVM LRKDLIDVKQ KIDKAIDKIS VFEKNKIISQ
YIGEKIYIKE DKFSGWFYFI IFTLILITIF IFIKAKVYKE KSEFDALTQI YNRGTIEKIL
NKKIKETDGS LIFFDIDHFK NINDNYGHEK GDLVLASLAR IIQKNIRSSD YFGRWGGEEF
VIILPQAPYE IAYKIAEKLR KIIEQTDFDG LNITISLGVS EFKKGDNPEV VLKKVDEALY
EAKNSGRNQV KGKK
//
