ID   B9LA04_NAUPA            Unreviewed;       649 AA.
AC   B9LA04;
DT   24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   24-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 86.
DE   SubName: Full=Mcp-signal transduction protein {ECO:0000313|EMBL:ACM93381.1};
GN   OrderedLocusNames=NAMH_1064 {ECO:0000313|EMBL:ACM93381.1};
OS   Nautilia profundicola (strain ATCC BAA-1463 / DSM 18972 / AmH).
OC   Bacteria; Campylobacterota; Epsilonproteobacteria; Nautiliales;
OC   Nautiliaceae; Nautilia.
OX   NCBI_TaxID=598659 {ECO:0000313|EMBL:ACM93381.1, ECO:0000313|Proteomes:UP000000448};
RN   [1] {ECO:0000313|EMBL:ACM93381.1, ECO:0000313|Proteomes:UP000000448}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1463 / DSM 18972 / AmH
RC   {ECO:0000313|Proteomes:UP000000448};
RX   PubMed=19197347; DOI=10.1371/journal.pgen.1000362;
RA   Campbell B.J., Smith J.L., Hanson T.E., Klotz M.G., Stein L.Y., Lee C.K.,
RA   Wu D., Robinson J.M., Khouri H.M., Eisen J.A., Cary S.C.;
RT   "Adaptations to submarine hydrothermal environments exemplified by the
RT   genome of Nautilia profundicola.";
RL   PLoS Genet. 5:E1000362-E1000362(2009).
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; CP001279; ACM93381.1; -; Genomic_DNA.
DR   RefSeq; WP_015902433.1; NC_012115.1.
DR   AlphaFoldDB; B9LA04; -.
DR   STRING; 598659.NAMH_1064; -.
DR   KEGG; nam:NAMH_1064; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_19_7; -.
DR   OrthoDB; 9781638at2; -.
DR   Proteomes; UP000000448; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR029150; dCache_3.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   InterPro; IPR029151; Sensor-like_sf.
DR   PANTHER; PTHR32089:SF112; HEME-BASED AEROTACTIC TRANSDUCER HEMAT; 1.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   Pfam; PF14827; dCache_3; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   SUPFAM; SSF103190; Sensory domain-like; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        294..316
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          318..372
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          377..634
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   COILED          602..629
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   649 AA;  72787 MW;  C876CA1392A4561B CRC64;
     MRFKDISISK KIHYPLIGAI IIGIIIMVVI SYTSTLNIKK EIFNNTKKDL ISLFNLKMEA
     KKDVGLTNSI AIAQNSAVIK ALQTGDREIA LKSLKNLTAY YKKYTKFKNI KIHIHTADLH
     SFLRVWKPNK HGDDLSGFRK TIVWVKEHKK PLVAIELGRA GLVLRGISPV IYNNQYLGSI
     EFMQGLNSIA KDLKKENIYT LIIFDKKYLN IATFLKNAPE IMQNYVLALK TGVYDINFFQ
     ELKNKKLQNI LKTENFFCVS IPIKDFSGNI VAYAILGKPL NLIEGAIKES ETTLIYQLIA
     MLIIDIFIVV ILMVIISKSV AKPIKELNER VEDLAEGEGD LTKKIMADSH DEIGTVSSNI
     NKFLDKLRNI INSLKELISQ TVSITNQTDK VTKKVKNSIE KQTKLLNNAK SFTQNIEEDV
     ESTKQIVLKT AEDIKNTQQV LEDLATSLNS IVTNIQNNTN QELEISNKVT MLADQSNQIK
     EIINIIKEIA DQTNLLALNA AIEAARAGEH GRGFAVVADE VRKLAERTQK SLSEIDSAIG
     IIVQGIMETQ SEIQNNAKDS EELSNIAYSL IEKSNNSMSK LNTTIEIADQ AKKESENIYN
     SIKELVKIID NLSKEADISK EAIKELNAIV SKLDSITKNL SNEVNNFKS
//