ID B9LNQ6_HALLT Unreviewed; 704 AA.
AC B9LNQ6;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Molybdopterin oxidoreductase {ECO:0000313|EMBL:ACM56994.1};
GN OrderedLocusNames=Hlac_1406 {ECO:0000313|EMBL:ACM56994.1};
OS Halorubrum lacusprofundi (strain ATCC 49239 / DSM 5036 / JCM 8891 / ACAM
OS 34).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Halorubraceae; Halorubrum.
OX NCBI_TaxID=416348 {ECO:0000313|EMBL:ACM56994.1, ECO:0000313|Proteomes:UP000000740};
RN [1] {ECO:0000313|EMBL:ACM56994.1, ECO:0000313|Proteomes:UP000000740}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34
RC {ECO:0000313|Proteomes:UP000000740};
RX PubMed=27617060; DOI=10.1186/s40793-016-0194-2;
RA Anderson I.J., DasSarma P., Lucas S., Copeland A., Lapidus A.,
RA Del Rio T.G., Tice H., Dalin E., Bruce D.C., Goodwin L., Pitluck S.,
RA Sims D., Brettin T.S., Detter J.C., Han C.S., Larimer F., Hauser L.,
RA Land M., Ivanova N., Richardson P., Cavicchioli R., DasSarma S.,
RA Woese C.R., Kyrpides N.C.;
RT "Complete genome sequence of the Antarctic Halorubrum lacusprofundi type
RT strain ACAM 34.";
RL Stand. Genomic Sci. 11:70-70(2016).
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- PATHWAY: Nitrogen metabolism. {ECO:0000256|ARBA:ARBA00004909}.
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. NasA/NapA/NarB subfamily.
CC {ECO:0000256|ARBA:ARBA00008747}.
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DR EMBL; CP001365; ACM56994.1; -; Genomic_DNA.
DR RefSeq; WP_015910136.1; NC_012029.1.
DR AlphaFoldDB; B9LNQ6; -.
DR GeneID; 7400725; -.
DR KEGG; hla:Hlac_1406; -.
DR eggNOG; arCOG01491; Archaea.
DR HOGENOM; CLU_000422_13_4_2; -.
DR Proteomes; UP000000740; Chromosome 1.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd00508; MopB_CT_Fdh-Nap-like; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 2.20.25.90; ADC-like domains; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR NCBIfam; NF041323; Nitr_red_NasA_Halo; 1.
DR PANTHER; PTHR43105:SF9; NITRATE REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15190)-RELATED; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Molybdenum {ECO:0000256|ARBA:ARBA00022505};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000000740}.
FT DOMAIN 2..60
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
FT REGION 678..704
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 704 AA; 74890 MW; B575AD2DA7047C59 CRC64;
MSEWTPTTCM RCAVGCGHLQ QGYTNNYGLD TVRGDASHPV NRGLACQRGV SETADPDGDW
LTRPLVREDG TLVPTSWETA IGTVVSHIED ALAETRDGVA VLGSGQQTNE AAYALGKLAR
GGFGTRYYDA NTTLCMASAV TAYYQAFGSD APPPTYEDIP DAETHVIWGA NPAVAHPVMY
RWIADSASDD DSELIVVDPV ESETVDDADL HAQVDPGTDL AFARAVLAQT VADDAVDREF
VAEATTGFEA TVDSLPSVRE AAETAGVSVE TVERVAEAMT DSALVYWGMG VNQSVQGTAT
SRALIDLCLA TGNLRPGSGP FSLTGQANSM GTRVCSSKGT WPGQRGFTDP EERQFIADEW
EIPRSRLPDD PGPGPVGIVD AVADGPPEVC WTVATNPVAG MPDASEVRSA LDDAFLVAQD
AFRTETVELA DVVLPAATWG ESEGTVTNME RRISRVRAAT ETSPKIKQDL DIIVAIGAAI
DGELFPRPAL SPESVFDELR ALTAGTPADL SGISYDRLEA ERAVRWPAPS PEAEGGYRYV
DNDGWSFPTP SGRARFSTGA HDGLAEPTDD EFPLTLTTGR QADAYNTGVR SRGTGTDDPP
MARIHPETTL EYIESFDRGK TVVSSRRGSV TIAVNPDDGV PKGMVWLPIH HPAVNALTLP
VVDPESDEPN LKQCAVDVRA PQPSNPLVHE GQPTVDGEPA PTDD
//
