ID B9Q0Z9_TOXGV Unreviewed; 226 AA.
AC B9Q0Z9; A0A0F7UPF2; B6KTM0; B9QHQ7; S7UKV6; S8GUC0;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=Transcription elongation factor 1 homolog {ECO:0000256|RuleBase:RU364033};
GN ORFNames=BN1205_054560 {ECO:0000313|EMBL:CEL72060.1}, TGVEG_297730
GN {ECO:0000313|EMBL:ESS29911.1};
OS Toxoplasma gondii (strain ATCC 50861 / VEG).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Sarcocystidae; Toxoplasma.
OX NCBI_TaxID=432359 {ECO:0000313|EMBL:ESS29911.1, ECO:0000313|Proteomes:UP000002226};
RN [1] {ECO:0000313|EMBL:ESS29911.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:ESS29911.1};
RA Paulsen I.;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50861 / VEG {ECO:0000313|Proteomes:UP000002226};
RA Lorenzi H., Inman J., Amedeo P., Brunk B., Roos D., Caler E.;
RT "Annotation of Toxoplasma gondii VEG.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ESS29911.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:ESS29911.1};
RA Sibley D., Venepally P., Karamycheva S., Hadjithomas M., Khan A., Brunk B.,
RA Roos D., Caler E., Lorenzi H.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:CEL72060.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:CEL72060.1};
RX PubMed=25875305; DOI=10.1371/journal.pone.0124473;
RA Ramaprasad A., Mourier T., Naeem R., Malas T.B., Moussa E., Panigrahi A.,
RA Vermont S.J., Otto T.D., Wastling J., Pain A.;
RT "Comprehensive Evaluation of Toxoplasma gondii VEG and Neospora caninum LIV
RT Genomes with Tachyzoite Stage Transcriptome and Proteome Defines Novel
RT Transcript Features.";
RL PLoS ONE 10:e0124473-e0124473(2015).
CC -!- FUNCTION: Transcription elongation factor implicated in the maintenance
CC of proper chromatin structure in actively transcribed regions.
CC {ECO:0000256|ARBA:ARBA00003357, ECO:0000256|RuleBase:RU364033}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU364033}.
CC -!- SIMILARITY: Belongs to the ELOF1 family.
CC {ECO:0000256|ARBA:ARBA00009730, ECO:0000256|RuleBase:RU364033}.
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DR EMBL; LN714491; CEL72060.1; -; Genomic_DNA.
DR EMBL; AAYL02000273; ESS29911.1; -; Genomic_DNA.
DR AlphaFoldDB; B9Q0Z9; -.
DR SMR; B9Q0Z9; -.
DR STRING; 432359.B9Q0Z9; -.
DR PaxDb; 5811-TGME49_097730; -.
DR EnsemblProtists; ESS29911; ESS29911; TGVEG_297730.
DR VEuPathDB; ToxoDB:TGVEG_297730; -.
DR eggNOG; KOG3214; Eukaryota.
DR OMA; CERINQP; -.
DR Proteomes; UP000002226; Partially assembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR Gene3D; 2.20.25.190; -; 1.
DR InterPro; IPR007808; Elf1.
DR InterPro; IPR038567; T_Elf1_sf.
DR PANTHER; PTHR20934:SF0; TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG; 1.
DR PANTHER; PTHR20934; UNCHARACTERIZED; 1.
DR Pfam; PF05129; Elf1; 1.
DR SUPFAM; SSF57783; Zinc beta-ribbon; 1.
PE 3: Inferred from homology;
KW Elongation factor {ECO:0000313|EMBL:ESS29911.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU364033};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364033};
KW Protein biosynthesis {ECO:0000313|EMBL:ESS29911.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002226};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU364033};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU364033};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU364033};
KW Zinc-finger {ECO:0000256|RuleBase:RU364033}.
FT REGION 89..226
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 113..141
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 151..216
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 226 AA; 25166 MW; 86B183CB432C0BAE CRC64;
MGKRKAKAMQ PKKNKLPKLD KEFDCPFCSH PRAVAVKMDR GRNIGTLGCR ICGTSYEKRI
NRLDEPIDIY GAWIDACVTA NTQAAEQAQK KMGSTLEGEE SVLESGVPVP SRKPRASREE
RPGVDSGDDL EFRRSPEASA DEEGEASEED VPRNSEEKRT GGARLKRLRK REESSEDEGS
DHVSGRDTDN AGQEDALRVL KTLREQQRNE EDAGSGRDEA LFEDDE
//
