ID B9S6T0_RICCO Unreviewed; 544 AA.
AC B9S6T0;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=AMP dependent ligase, putative {ECO:0000313|EMBL:EEF40686.1};
DE EC=6.2.1.26 {ECO:0000313|EMBL:EEF40686.1};
GN ORFNames=RCOM_0873340 {ECO:0000313|EMBL:EEF40686.1};
OS Ricinus communis (Castor bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Euphorbiaceae; Acalyphoideae; Acalypheae;
OC Ricinus.
OX NCBI_TaxID=3988 {ECO:0000313|Proteomes:UP000008311};
RN [1] {ECO:0000313|Proteomes:UP000008311}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Hale {ECO:0000313|Proteomes:UP000008311};
RX PubMed=20729833; DOI=10.1038/nbt.1674;
RA Chan A.P., Crabtree J., Zhao Q., Lorenzi H., Orvis J., Puiu D.,
RA Melake-Berhan A., Jones K.M., Redman J., Chen G., Cahoon E.B., Gedil M.,
RA Stanke M., Haas B.J., Wortman J.R., Fraser-Liggett C.M., Ravel J.,
RA Rabinowicz P.D.;
RT "Draft genome sequence of the oilseed species Ricinus communis.";
RL Nat. Biotechnol. 28:951-956(2010).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}.
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
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DR EMBL; EQ973882; EEF40686.1; -; Genomic_DNA.
DR AlphaFoldDB; B9S6T0; -.
DR STRING; 3988.B9S6T0; -.
DR eggNOG; KOG1176; Eukaryota.
DR InParanoid; B9S6T0; -.
DR Proteomes; UP000008311; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0008756; F:o-succinylbenzoate-CoA ligase activity; IEA:UniProtKB-EC.
DR CDD; cd12118; ttLC_FACS_AEE21_like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43859; ACYL-ACTIVATING ENZYME; 1.
DR PANTHER; PTHR43859:SF5; ISOVALERATE--COA LIGASE AAE2-RELATED; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:EEF40686.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008311}.
FT DOMAIN 20..404
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 454..528
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 544 AA; 59979 MW; 9EF815735C7B884A CRC64;
MEGLVCCSTN YVPLSPTSFL ERAAKVYRDR TSVVYGDVKY SWSGTYDRCV KLASALAQLG
ISHGDVVATL APNVPAMYEL HFAVPMAGGV LCTLNTRYDS NMVSILLDHS EAKIIFVDFQ
LLDVASKALE LLANTERKSP IVVLISESDG LSPTGFTSNT YEYESLLANG NKGFEIRRPK
NEWDPISVNY TSGTTSRPKG VVYSHRGAYL NSLATVFLHG IGAMPVYLWT VPMFHCNGWC
LTWGVAAQGG TNICIRKVTP KAIFDSIGQH NVTHMGGAPT VLNMIVNSPV SDRRTLPHKV
EIMTGGAPPP PQIIFKMEEL GFGVSHLYGL TETYGPGTYC AWKPEWDSLP PDERAKLKAR
QGIHHLGLED VDVRDPMTQE SVPADGKTIG EIVFRGNTVM SGYLKDLKAT EEAFQGGWFR
SGDLAVKHPD GYIEVKDRLK DIIISGGENI STVEVETVLY SHPAIFEAAV VARPDDHWGQ
TPCAFVKLKE GFVVSEQDII KFCRDRLPHY MAPRTVIFED LPRTSTGKVQ KFILRQKAKA
TENL
//
