ID B9TEJ9_RICCO Unreviewed; 450 AA.
AC B9TEJ9;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 24-JAN-2024, entry version 54.
DE SubName: Full=Glucosylceramidase, putative {ECO:0000313|EMBL:EEF25715.1};
DE EC=3.2.1.75 {ECO:0000313|EMBL:EEF25715.1};
GN ORFNames=RCOM_1936910 {ECO:0000313|EMBL:EEF25715.1};
OS Ricinus communis (Castor bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Euphorbiaceae; Acalyphoideae; Acalypheae;
OC Ricinus.
OX NCBI_TaxID=3988 {ECO:0000313|Proteomes:UP000008311};
RN [1] {ECO:0000313|Proteomes:UP000008311}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Hale {ECO:0000313|Proteomes:UP000008311};
RX PubMed=20729833; DOI=10.1038/nbt.1674;
RA Chan A.P., Crabtree J., Zhao Q., Lorenzi H., Orvis J., Puiu D.,
RA Melake-Berhan A., Jones K.M., Redman J., Chen G., Cahoon E.B., Gedil M.,
RA Stanke M., Haas B.J., Wortman J.R., Fraser-Liggett C.M., Ravel J.,
RA Rabinowicz P.D.;
RT "Draft genome sequence of the oilseed species Ricinus communis.";
RL Nat. Biotechnol. 28:951-956(2010).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 30 family.
CC {ECO:0000256|ARBA:ARBA00005382}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; EQ979064; EEF25715.1; -; Genomic_DNA.
DR AlphaFoldDB; B9TEJ9; -.
DR STRING; 3988.B9TEJ9; -.
DR eggNOG; KOG2566; Eukaryota.
DR InParanoid; B9TEJ9; -.
DR Proteomes; UP000008311; Unassembled WGS sequence.
DR GO; GO:0052859; F:glucan endo-1,4-beta-glucosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0046557; F:glucan endo-1,6-beta-glucosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0004348; F:glucosylceramidase activity; IEA:InterPro.
DR GO; GO:0006665; P:sphingolipid metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR033452; GH30_C.
DR InterPro; IPR001139; Glyco_hydro_30.
DR InterPro; IPR033453; Glyco_hydro_30_TIM-barrel.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR11069; GLUCOSYLCERAMIDASE; 1.
DR PANTHER; PTHR11069:SF23; LYSOSOMAL ACID GLUCOSYLCERAMIDASE; 1.
DR Pfam; PF02055; Glyco_hydro_30; 1.
DR Pfam; PF17189; Glyco_hydro_30C; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000313|EMBL:EEF25715.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EEF25715.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008311};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 7..273
FT /note="Glycosyl hydrolase family 30 TIM-barrel"
FT /evidence="ECO:0000259|Pfam:PF02055"
FT DOMAIN 276..331
FT /note="Glycosyl hydrolase family 30 beta sandwich"
FT /evidence="ECO:0000259|Pfam:PF17189"
FT REGION 342..367
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 427..450
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 435..450
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 450 AA; 48998 MW; C1AB1C84AA9D9F15 CRC64;
MPPGQGDPQL KHFSIDPQKA TVLPTVKAAL AINPHLKVIA SPWSAPGWMK TSDSLVKGTL
KPEAFDAFAR YLGRYVAAMR DQGVTISALT LQNEPHFEPD NYPGMRVDPH KRAAFIRDHL
GPLLARSHPG TAIFDWDHNW DEPESPAVVL SDPRAAKYVS GVAWHCYGGD VRAQGRLHDL
FPAKDTWFTE CSGGRWAPDW AKNLQYFAKT LVIDTTRNWA RGVLFWNLAL DAHDGPHLGG
CNDCRGVVTI DAATGAVTRN VEYYALAHAS RFVLPGAHRI ASTGENNVAF VNPDGSYALL
VANGDAQPRA LAVRVGTQAF RYTLPASSVA TQPPPLAVCL GPKTPPTGET SVNHQGRSPP
GRGRPGHRIA RRARQGIGVA GQAGTRAEGH RRTRLPAVAR GALPVVRHVA HDRRVHPPVV
RHLLHVDPAD HRHGTARRRH AHDGGVRRQP
//
