ID B9WGE9_CANDC Unreviewed; 775 AA.
AC B9WGE9;
DT 24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT 24-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Topoisomerase II-associated deadenylation-dependent mRNA-decapping factor, putative {ECO:0000313|EMBL:CAX42323.1};
GN OrderedLocusNames=Cd36_44510 {ECO:0000313|CGD:CAL0000169672};
GN ORFNames=CD36_44510 {ECO:0000313|EMBL:CAX42323.1};
OS Candida dubliniensis (strain CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 /
OS NRRL Y-17841) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=573826 {ECO:0000313|EMBL:CAX42323.1, ECO:0000313|Proteomes:UP000002605};
RN [1] {ECO:0000313|EMBL:CAX42323.1, ECO:0000313|Proteomes:UP000002605}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 / NRRL Y-17841
RC {ECO:0000313|Proteomes:UP000002605};
RX PubMed=19745113; DOI=10.1101/gr.097501.109;
RA Jackson A.P., Gamble J.A., Yeomans T., Moran G.P., Saunders D., Harris D.,
RA Aslett M., Barrell J.F., Butler G., Citiulo F., Coleman D.C.,
RA de Groot P.W.J., Goodwin T.J., Quail M.A., McQuillan J., Munro C.A.,
RA Pain A., Poulter R.T., Rajandream M.A., Renauld H., Spiering M.J.,
RA Tivey A., Gow N.A.R., Barrell B., Sullivan D.J., Berriman M.;
RT "Comparative genomics of the fungal pathogens Candida dubliniensis and
RT Candida albicans.";
RL Genome Res. 19:2231-2244(2009).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, P-body
CC {ECO:0000256|ARBA:ARBA00004201}.
CC -!- SIMILARITY: Belongs to the PAT1 family.
CC {ECO:0000256|ARBA:ARBA00009138}.
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DR EMBL; FM992691; CAX42323.1; -; Genomic_DNA.
DR RefSeq; XP_002420103.1; XM_002420058.1.
DR AlphaFoldDB; B9WGE9; -.
DR GeneID; 8047935; -.
DR KEGG; cdu:CD36_44510; -.
DR CGD; CAL0000169672; Cd36_44510.
DR VEuPathDB; FungiDB:CD36_44510; -.
DR eggNOG; KOG4592; Eukaryota.
DR HOGENOM; CLU_012622_1_0_1; -.
DR OrthoDB; 2786412at2759; -.
DR Proteomes; UP000002605; Chromosome 4.
DR GO; GO:0000932; C:P-body; IEA:UniProtKB-SubCell.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR GO; GO:0000290; P:deadenylation-dependent decapping of nuclear-transcribed mRNA; IEA:InterPro.
DR InterPro; IPR039900; Pat1-like.
DR InterPro; IPR019167; PAT1_dom.
DR PANTHER; PTHR21551:SF0; PROTEIN ASSOCIATED WITH TOPO II RELATED-1, ISOFORM A; 1.
DR PANTHER; PTHR21551; TOPOISOMERASE II-ASSOCIATED PROTEIN PAT1; 1.
DR Pfam; PF09770; PAT1; 2.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Isomerase {ECO:0000313|EMBL:CAX42323.1}.
FT DOMAIN 63..496
FT /note="mRNA decay factor PAT1"
FT /evidence="ECO:0000259|Pfam:PF09770"
FT DOMAIN 498..763
FT /note="mRNA decay factor PAT1"
FT /evidence="ECO:0000259|Pfam:PF09770"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 57..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 93..315
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 61..76
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 110..131
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 147..202
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 203..230
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 239..280
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 290..315
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 775 AA; 87315 MW; 5E5E670456B82399 CRC64;
MSFFGFDPAA PPQGANQKDD VYDFENTYDG LGELQEDDAF NQETFGTSTS EIRKDFEFSQ
GESQQSESYA KASAPPAQTI SYAQAATVPV NDDEFMQELW GSSNAPSKNH TDSTEEKTAG
GQSEKKILSL EEIEAQLTAI DPSQQPPLPQ QQFPPQPYGV PGMMPPPPQF GYMMAPGFMP
PQYPYPGMIP QQMPPMQQGQ FPPPQPQQQQ QQQQQQPQPQ QQQQTAGPVD KQVSEGPARS
PASKKTQKVD LSNFPVLGSK EAQSHQQSTP QQQVQSQQQR HHHHYNQHYQ HGHQREPSQE
LTPEQQEKAA RRQEKVSRIM KYSGIMNPKD KDFVTRFQLS QIVTEDPYNE DFYAQVFKVI
HPKTINGAQQ STQQNNSIAQ AYLDHSGHRL GGRYKRADVA LQRMQQQVQK AVTVAKERPK
LTQYAKEGAL GKISFGSGKK PRQQLEIISK AAERQKQENQ IGKKEGVKHY SKKDILSILE
NIIGELMNVE SESRTRADVD TSKLWESLKV LEQSSSSGDE ESEVNPFIQC LNYNKMLKIL
LRLFKFLTRE QILTIVTLIM SNLENLLVIK NGSYTTYPNK KVPENIVKLV EAYTLTFSKV
LMNAVLDFKF NEIIGLLVIL IEHNNVSFVS TTKIGLSILT TLLSRAELII GEGSISATDL
SEWSSCYDEL FTSLESRIAA IFPPNPEDVD DGSSGENYIW QFLATLSLGG KLSHQRIIVD
EVRDEIFCVM NRAKAIANTD MANLYKKQNL LNNLNMYLVV MGLVADETEI KELQQ
//
