ID   B9WGR5_CANDC            Unreviewed;       697 AA.
AC   B9WGR5;
DT   24-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   24-MAR-2009, sequence version 1.
DT   24-JAN-2024, entry version 67.
DE   SubName: Full=Golgi apyrase, putative {ECO:0000313|EMBL:CAX42441.1};
GN   OrderedLocusNames=Cd36_45750 {ECO:0000313|CGD:CAL0000160002};
GN   ORFNames=CD36_45750 {ECO:0000313|EMBL:CAX42441.1};
OS   Candida dubliniensis (strain CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 /
OS   NRRL Y-17841) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=573826 {ECO:0000313|EMBL:CAX42441.1, ECO:0000313|Proteomes:UP000002605};
RN   [1] {ECO:0000313|EMBL:CAX42441.1, ECO:0000313|Proteomes:UP000002605}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 / NRRL Y-17841
RC   {ECO:0000313|Proteomes:UP000002605};
RX   PubMed=19745113; DOI=10.1101/gr.097501.109;
RA   Jackson A.P., Gamble J.A., Yeomans T., Moran G.P., Saunders D., Harris D.,
RA   Aslett M., Barrell J.F., Butler G., Citiulo F., Coleman D.C.,
RA   de Groot P.W.J., Goodwin T.J., Quail M.A., McQuillan J., Munro C.A.,
RA   Pain A., Poulter R.T., Rajandream M.A., Renauld H., Spiering M.J.,
RA   Tivey A., Gow N.A.R., Barrell B., Sullivan D.J., Berriman M.;
RT   "Comparative genomics of the fungal pathogens Candida dubliniensis and
RT   Candida albicans.";
RL   Genome Res. 19:2231-2244(2009).
CC   -!- SIMILARITY: Belongs to the GDA1/CD39 NTPase family.
CC       {ECO:0000256|ARBA:ARBA00009283, ECO:0000256|RuleBase:RU003833}.
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DR   EMBL; FM992691; CAX42441.1; -; Genomic_DNA.
DR   RefSeq; XP_002420218.1; XM_002420173.1.
DR   AlphaFoldDB; B9WGR5; -.
DR   GeneID; 8047739; -.
DR   KEGG; cdu:CD36_45750; -.
DR   CGD; CAL0000160002; Cd36_45750.
DR   VEuPathDB; FungiDB:CD36_45750; -.
DR   eggNOG; KOG1386; Eukaryota.
DR   HOGENOM; CLU_010246_3_3_1; -.
DR   OrthoDB; 180318at2759; -.
DR   Proteomes; UP000002605; Chromosome 4.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProt.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0017110; F:nucleoside diphosphate phosphatase activity; IEA:UniProt.
DR   Gene3D; 3.30.420.40; -; 1.
DR   Gene3D; 3.30.420.150; Exopolyphosphatase. Domain 2; 1.
DR   InterPro; IPR000407; GDA1_CD39_NTPase.
DR   PANTHER; PTHR11782; ADENOSINE/GUANOSINE DIPHOSPHATASE; 1.
DR   PANTHER; PTHR11782:SF121; NUCLEOSIDE-DIPHOSPHATASE MIG-23; 1.
DR   Pfam; PF01150; GDA1_CD39; 1.
DR   PROSITE; PS01238; GDA1_CD39_NTPASE; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|PIRSR:PIRSR600407-2};
KW   Hydrolase {ECO:0000256|RuleBase:RU003833};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|PIRSR:PIRSR600407-2};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        519..537
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          676..697
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        158
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR600407-1"
FT   BINDING         194..198
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR600407-2"
SQ   SEQUENCE   697 AA;  78753 MW;  33CAA3F2B6E4953B CRC64;
     MSNLKRSDNS NEKYGIVIDS GSSGSRIQIY KWTDQQFELK SSKDQSVLQS PPKITQEKGW
     TKKITPGIST YNSKDKSGRI WQDHYSELLK FAEDIIPSDK QPDTPVFVLS TAGMRLLSKK
     DQKSILKETC SGIKQNTNFY IPTENCENFV EIIDGSTEGI YGWLGLNYLM KQFNNYDSSQ
     DSLHESIGFM DMGGASTQIA FVPSSKEEVI KHKEDLSTVT LRNINGETQT WDLFVATWLG
     FGANEARKRF LNQLINLAIV NGENWNNEIN DPCLPKGASM KYEHEKKQYL VQGVGNYEMC
     IKTIYPLLMK NMVCIDEPCL FNGIHGPKFN FEKDKFIGIS EYWYTANDIF QSGGEYNFKA
     FNAKVKEYCE SNWDDILKNS KQGQYSNLDP DKFLKDACFK ASWVMNILHE GFELPRIGFE
     TEKEDQTEED KKITNSHVPF KSADSVEGEE LSWTLGKILL FASSQIEPKE GDADAKQIGI
     YPSEISGRKF VPGGGSLSGE GDYSTDDEDD DFGSQFSHIL YSLIFIFLLL FFLFHFGKSH
     FGRWSNKLRR FQIPVEVKRA VNTIGSKIPG VRHYFENIVM FSDLQDQSII LEEGIFDNTS
     NNTNFKTLQN QQQPASASVL RTRSAIGLNE NSGNDYKGGS GQSLTNLSSY NPKGNSYYNK
     SFSSPKKNIY ISANNSRESL ARGSSNASIP RSKSSLD
//